Reproductive Health Flashcards
What is infertility
Inability to naturally conceive a child is called infertility
Causes of infertility in males + Remedy
Poor sperm production (less in number or defective sperms)
- Azoospermia (no sperm cells are produced)
- Oligospermia (few sperm cells are produced)
Remedy: Testes stimulated by Testosterone injections
Causes of infertility in females
- Poor egg production
- Blockage between egg and sperm
- Hostile response to sperm
What leads to poor egg production?
- Hormonal changes result in less number of follicle cells
- Follicular cells are unable to mature into one graafian follicle (PCOD- Polycystic Ovarian Disorder)
- Fimbriae is unable to pick up released ovum from the ovary
Remedy: Poor egg production
- Pills are given to stimulate the pituitary gland and ovaries to release adequate amount of hormones
- Gonadotropin injections are given
What causes blockage between egg and sperm?
- Cervical mucus is too thick and the sperms are not allowed to enter the uterus
- Blockage of the fallopian tube due to inflammation or infection
- Damaged lining of the fallopian tube prevents it from propelling the fertilized egg to the uterus for implantation (Tube pregnancy/Ectopic pregnancy)
Remedy: Blockage between egg and sperm
Surgery is the only remedial measure
What causes hostile response to sperm?
The woman’s body produces anti-sperm antibodies (allergic response) against the sperm that enter the reproductive tract.
(NK cells- Natural killer cells that destroy the sperm)
Remedy: Hostile response to sperm
Immuno-suppressive drugs are administered
ART full form
Assisted Reproductive Technologies
Artificial insemination
Semen is introducedinto the vagina or uterus of the female (IUI- Intra-uterine insemination)
IVF
In-Vitro Fertilization
- The eggs are removed from the female and mixed with the semen in a test tube
- It is monitored for fertilization and embryogenesis
- Usually at the 8 celled stage (morula), the embryo is transferred ito the uterus of the female
GIFT
Gamete Intra-fallopian transfer
Eggs and sperms are collected and then transfered into the fallopian tube
Fertilization takes place In-Vivo
ZIFT
Zygote Intra-fallopian transfer
The fertilized egg with up to 8 blastomeres are transferred into the fallopian tube
IUT
Intra-Uterine Transfer
The embryo at 8 blastomeres stage is introduced directly into the uterus
Fertilization is In-Vitro
ICSI
Intra Cytoplasmic Sperm Injection
- The sperm is directly injected into the ovum
- Fertilization is In-Vitro
- The embryo is then transferred either into the fallopian tube or uterus of the female