Human Health and Diseases Flashcards
Secondary infection
Infection that occurs during or after the treatment of an infection (primary infection)
Disease by one pathogen + another disease by different pathogen
Reinfection
Getting infected by the same pathogen again
Nosocomial infection
Hospital-borne infection
Pathogen
Infection or disease causing microorganism
Pathogenicity
The ability of a pathogen to cause an infection/disease is called pathogenicity
Virulence
The degree of pathogenecity is called virulence
Invasiveness
Ability of the pathogen to invade the body cells and colonise
Toxigenecity
The ability of a pathogen to produce a toxin which can cause infection/disease
Incubation period
The time period between the entry of the pathogen and the development of the first visible symptom
Epidemiology
The study of occurrence and prevalence of a disease is termed as epidemiology
Sporadic disease
Restricted to a particular (small) group of people
E.g. Food poisoning
Endemic disease
Restriced to a particular area
E.g. NEPA virus in Kerala
Epidemic disease
Rapid spread of disease in a given population within a short period of time
E.g. Cholera
Pandemic disease
Spread of a particular disease across the world
E.g. AIDS, Ebola virus, Corona virus, Smallpox, Polio (eradicated in 2018)
Direct modes of transmission of pathogenic microorganisms
- Contact
- Droplet
- Soil
- Transplacental
Direct mode of transmission- Contact
STDs- Sexually transmitted diseases
E.g. AIDS
AIDS is caused:
1. through sexual contact
2. infected needles and infected blood
3. transplacental (mother to foetus)
Direct mode of transmission- Droplet
E.g. Diptheria and Tuberculosis
Direct mode of transmission- Soil
Ringworm infection (Fungal/Mycotic infection)
All soil borne infections are usually mycotic infections
Direct mode of transmission- Transplacental
Hepatitis B (inflammation of liver)
Hepatitis A and Hepatitis C are water-borne
Indirect modes of transmission of pathogenic microorganisms
- Vectors
- Vehicle borne
- Fomite borne
- Airborne
Vectors- types
- Mechanical vector
- Biological vector
What are mechanical vectors + examples
Mechanical vectors pick up pathogens on the outside of their bodies and transmit them through physical contact
E.g. Tsetse fly carries Trypanosoma which causes African sleeping sickness
E.g. Aedes mosquito carries Flavivirus which cause Dengue
What are biological vectors + examples
One part of the life cycle of the pathogen takes place in the carriers or vectors and the other part of the life cycle takes place in the host
E.g. Female anopholes mosquito carries Plasmodium (underline) causing Malaria
Vehicle borne
Water or milk
E.g. Water- Cholera
Fomite borne
Fomite- Inanimate objects which are used by the infected person are called fomite
E.g. Chickenpox
Diphtheria-
Causative agent
Mode of transmission
BACTERIAL DISEASE
Corynebacterium diptheriae (UNDERLINE)
Mode of transmission: Droplet infection
Diphtheria:
Symptoms
BACTERIAL DISEASE
Symptoms:
1. Fever and chills
2. Rapid rate of breathing, noisy breathing (because bacteria colonise in the throat)
3. Sore throat, swollen lymph nodes, difficulty in swallowing
Diphteria:
Prevention/Treatment
BACTERIAL DISEASE
- Healthy lifestyle
- Well ventilated room
- Avoid contact with sick people
- Avoid congested, polluted places
- DPT vaccine: mandatory for babies. Diphtheria, Petrussis, Tetanus
Pneumonia
Causative agent
Mode of transmission
BACTERIAL DISEASE
Causative agent: Streptococcus pneumoniae (UNDERLINE)
Mode of transmission: Inhalation of droplets
Pneumonia symptoms
BACTERIAL DISEASE
- PERSISTENT dry cough
- High fever
- Rapid rate of breathing
- Sputum (spit containing microoganisms) contains streaks of blood
Pneumonia
Prevention/Treatment
BACTERIAL DISEASE
- Well ventilated room
- Healthy lifestyle
- Avoid contact with sick people
Typhoid
Causative agent
Mode of transmission
BACTERIAL DISEASE
Causative agent: Salmonella typhi (UNDERLINE)
Mode of transmission: Contaminated water or food
Typhoid
Symptoms
BACTERIAL DISEASE
- Sustained high fever (ENTERIC)
- Abdominal pain
- Constipation
- Diarrhoea
- Loss of appetite
Why is typhoid fever called enteric fever?
Because Salmonella typhi the causative agent colonises in the enteric region i.e. intestinal region of the body
Typhoid:
Prevention/Treatment
BACTERIAL DISEASE
- Filtered/boiled and cooled water
- Wash vegetables/fruits before consumption
Plague:
Causative agent
Mode of transmission
BACTERIAL DISEASE
Causative agent: Yersinia pestis (UNDERLINE)
Mode of transmission: Flea bite
Plague
Symptoms
BACTERIAL DISEASE
- Fever
- Chills
- Fatigue
- Swollen lymph nodes
Plague
Prevention/Treatment
BACTERIAL DISEASE
- Live in hygienic conditions
- Remove clutter from homes
- Rodent free homes and surroundings
Tinea
Causative agent
Mode of transmission
RINGWORM INFECTION
Causative agent:
Microsporium
Trichophyton
Epidermophyton
(UNDERLINE)
Mode of transmission
When moist, warm area of the body comes in contact with the soil or contaminated fomite
Tinea symptoms
RINGWORM INFECTION
1. Mild irritation
2. Patch of inflammation
3. Scaling
4. Hair loss
Tinea prevention/treatment
RINGWORM INFECTION
1. Keep junctures of body parts dry
2. Personal hygiene
3. Wearing proper footwear
4. Avoid wearing tight fitting clothes
Common cold/Rhinitis
Causative agent
Mode of transmission
VIRAL DISEASE
Causative agent: Cold viruses
Mode of transmission:
Fomite infection
Droplet infection
Common cold/Rhinitis
Symptoms
VIRAL DISEASE
- Nasal congestion and discharge
- Sore throat, dry cough
- Headache and stuffy feeling in the head
- Difficulty in breathing
Common cold/Rhinitis
Prevention/treatment
VIRAL DISEASE
1. Proper personal hygiene
2. Rehydration
3. Steam inhalation
4. Cover the mouth and nose while coughing or sneezing
Chikungunya
causative agent
mode of infection
VIRAL DISEASE
causative agent: Alpha virus
mode of infection: bite of Aedes aegypti (UNDERLINE) mosquito (acts as a mechanical vector)
Chikungunya
Symptoms
VIRAL DISEASE
- Arthralgic disease affecting the joints of extremities
- Myalgia i.e. pain in muscles
- Generalised rash, nausea, fatigue
Chikungunya
Prevention/treatment
VIRAL DISEASE
- Stagnant water to be removed
- Do not allow breeding of mosquitoes
- Mosquito net
- Intake of adequate amount of water
Dengue fever
Causative agent
Mode of transmission
VIRAL DISEASE
Causative agent: Flavivirus (UNDERLINE)
Mode of transmission: Bite of the female Aedes mosquito
Dengue fever
symptoms
VIRAL DISEASE
1. Break bone fever- Severe pain in the bones and painful spasms
2. Rash, muscle and joint paint, headache (behind the eyes)
3. Flushed skin
4. Internal bleeding in the gut
Dengue fever
Clinical manifestations
- Thrombocytopenia- low platelet count
- Interferon release- Interferons are anti-viral proteins released by the immune system during a viral infection to fight against the invading virus
- Capillary permeability
Dengue fever
Prevention/treatment
VIRAL DISEASE
- Stagnant water to be removed
- Do not allow breeding of mosquitoes
- Mosquito net
- Intake of adequate amount of water
Ascariasis
Causative agent
Mode of transmission
DISEASE CAUSED BY HELMINTHS
Causative agent: Ascaris lumbricoides (UNDERLINE)
Mode of transmission: Contaminated food or water
Ascariasis
Symptoms
DISEASE CAUSED BY HELMINTHS
1. Vomiting
2. Abdominal cramps and pain (around the naval, radiating to the lower abdomen)
3. Intestinal obstruction
4. Biliary obstruction
Ascariasis
Prevention/treatment
DISEASE CAUSED BY HELMINTHS
1. Proper sanitary hygiene
2. Filtered, boiled and cooled water
3. Wash vegetables/fruits before consumption
Filariasis/Elephantiasis
Causative agent
Mode of transmission
DISEASE CAUSED BY HELMINTHS
Causative agent: Wuchereria bancrofti
Exhibits sexual dimorphism- female larger than male
Rhabditiform larva stage of the life cycle takes place in the man
Mode of transmission: Bite of Culex mosquito (Biological vector)
Filariasis/Elephantiasis
Symptoms
DISEASE CAUSED BY HELMINTHS
1. Inflammation of lymph glands and nodes
2. Enlargement of limbs
3. Blockage of lymphatic circulation
Filariasis/Elephantiasis
Prevention/treatment
DISEASE CAUSED BY HELMINTHS
1. Stagnant water to be removed
2. Do not allow breeding of mosquitoes
3. Mosquito nets
4. Intake of adequate amount of water
Amoebiasis
Causative agent
Mode of transmission
PROTOZOAN DISEASE
in chronic stages it is termed as amoebic dysentery
Causative agent: Entamoeba histolyca
Mode of transmission: Contaminated by food or water
Amoebiasis
Symptoms
PROTOZOAN DISEASE
1. Intermittent or profuse diarrhoea
2. Abdominal cramping- on or around the navel
3. Fever
4. Abdominal pain- generalised
Amoebiasis
Prevention/Treatment
PROTOZOAN DISEASE
1. Proper personal hygiene
2. Proper intake of water
3. Filtered, boiled and cooled water
4. Washed vegetables/fruits before consumption
Malaria
Causative agent
Mode of transmission
PROTOZOAN DISEASE
Causative agents:
* Plasmodium vivax (most fatal)
* Plasmodium ovale
* Plasmodium falciparum
* Plasmodium malaria
Mode of transmission: Bite from female anopheles mosquito
Malaria
Symptoms
PROTOZOAN DISEASE
1. Bouts of high fever with bed-shaking shivers
2. Headache and nausea
3. Muscle pain
4. Liver abscess
Malaria
Prevention/Treatment
PROTOZOAN DISEASE
1. Stagnant water to be removed
2. Do not allow breeding of mosquitoes
3. Mosquito nets
4. Intake of adequate amount of water