Repro Ex III PART TRES (mostly testes) Flashcards

1
Q

What is the tumor marker for the yolk sac tumor of infancy produce?

A

AFP-Alpha FetoProtein

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2
Q

What is the homologous tumor of the yolk sac tumor?

A

Endodermal Sinus Tumor in the ovary

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3
Q

Which is more severe: an embryonal carcinoma or Seminoma?

A

Embryonal carcinoma is more aggressive and lethal then a Seminoma

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4
Q

What 8 tissues can be found in a testicular teratoma? DO I find teeth like the female germ cells tumors?

A

1.neural 2.skeletal 3.cartilage 4.thyroid 5.respiratory 6.epithelium 7.Squamous epi 8.GI tract..no teeth :(

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5
Q

How does age of the Pt relate to malignancy in a Testicular Teratoma?

A

The older and more mature the teratoma the more malignant.

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6
Q

What is the female equivalent to the Testicular Teratoma?

A

The Dermoid Cyst/ovarian teratoma

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7
Q

What are the two hormone producing tumors of the testies? What do they secrete?

A
  1. Leydig Cell Tumor/Interstitial Cell Tumor (androgens, estrogens, or both) 2.Sertoli Cell Tumor (mostly estrogen, some androgen)
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8
Q

What is the tumor that is a highly malignant testicular tumor, which represents germ cell extraembryonic differentiation to the components of the placenta, namely, cyto and syncytiotrophoblast?

A

A Choricocarcinoma!

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9
Q

Which tumor has no testicular enlargement and is detected as a small, painless nodule?

A

a choriocarcinoma

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10
Q

Which tumor am I? Microscopically, the trophoblastic tissues are found in the areas of hemorrhage.

A

a choriocarcinoma

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11
Q

What is a marker for a choriocarcinoma?

A

hCG

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12
Q

What cancer represents the most common urinary tract neoplasm?

A

Cancer of the Urinary Bladder

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13
Q

What is the EGYPTIAN parasite that has been linked to causing bladder cancer?

A

Sc-hist-o-soma Hae-mat-o-bium

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14
Q

Which prostate tumor markers are made by the prostate itself? Which marker is made elsewhere?

A

PSA and PAP are made by the prostate….Alkaline Phosphatase made by osteoblasts in the bone

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15
Q

What are the two markers that would indicate in an old man that prostate cancer has metastasized to the bone?

A

PAP and Alkaline phosphatase

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16
Q

What does BPH stand for?

A

Benign Prostatic Hyperplasia

17
Q

What type of cancer is prostate cancer?

A

Adenocarcinoma (the prostate is a gland!)

18
Q

Who is most likely to get BPH???It is most frequent in Western Europe and the ___ and least common in the ______. The prevalence is higher among U.S. _____ than whites and the disease peaks at about ___ years.
75% of men over 80 years of age have some degree of BPH. It is rare to see this disease in men younger than _____.

A

U.S…..Orient…blacks…70 years…40 years

19
Q

What is the pathogenesis of BPH?

A

Testosterone plays a crucial role, castration stopped development of BPH

20
Q

DOES BPH PROGRESS TO CANCER?

A

no (at least the almighty NIH says so)

21
Q

What does TURP stand for?

A

TransUrethral Resection of the Prostate

22
Q

Which ethnic group has the highest risk for BPH? Prostate Cancer?

A

Blacks & Blacks

23
Q

The prostate contains about 30-50 individual compound tubuloalveolar ____, each gland having its own duct that delivers the secretory product to the ________.

A

glands…prostatic urethra

24
Q

The prostate is about the size of a _______, and secretes an _______ fluid and constitutes 13-33% of semen.

A

chestnut…alkaline

25
Q

The prostate is a single _______-shaped gland that lies inferior to the urinary bladder and surrounds the upper portion of the urethra.

A

doughnut

26
Q

What type of epithelium lines the prostate gland?

A

simple–>pseudo stratified columnar epithelium

27
Q

What are the lumens of the prostate gland usually surrounded by? (composed of calcified glycoproteins)

A

CORPORA AMYLACEA

28
Q

What organism causes acute prostatitis? What host cell is going to show up first?

A

E.Coli….PMNs

29
Q

What are the 3 hallmark cells of chronic bacterial prostatitis?

A

Lymphocytes, Plasma Cells, Macrophages

30
Q

What 2 organisms are most likely to cause granulates prostatitis?

A

1.Mycobacterium tuberculosis and 2. Histoplasma capsulatum

31
Q

What is a good GLEASON score? What is a bad score? What are the majority of prostate cancers?

A

Majority pattern (1-5) + minority pattern (1-5)….BEST score 2….WORST score 10…majority of prostate cancers are 4-7

32
Q

Both malignant and ______ prostatic cells express a specific antigen called Prostate Specific Antigen (PSA).

A

NORMAL!

33
Q

The PSA levels in the serum usually correlate with the cancer _______.

A

volume