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Reproduction > Exam I review part 1 (embryo, histo, malformations) > Flashcards

Exam I review part 1 (embryo, histo, malformations) Flashcards

1
Q

Name that HOMOLOGUE! Structure: Gonads…M?F?

A

Gonads: M-Testes F-Ovaries

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2
Q

Name that HOMOLOGUE! Structure: Genital tubercle…M?F?

A

Genital tubercle: M-Penis F-Clitoris

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3
Q

Name that HOMOLOGUE! Structure: Urethral/genital swellings…M? F?

A

Urethral/genital Swellings: M-Scrotum F-Labia Majora

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4
Q

Name that HOMOLOGUE! Structure:Urethral folds…M?F?

A

Urethral folds: M- Spongy urethra F-Labia Minora

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5
Q

Name that HOMOLOGUE! Structure: UroGential sinus M-Prostate F-?

A

Skeens glands

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6
Q

Name that HOMOLOGUE! Structure: UroGenital sinus F- Bartholin’s glands..M?

A

Cowper’s glands

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7
Q

Name that HOMOLOGUE! Structure: UroGenital sinus M-Bladder..F?

A

Bladder

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8
Q

Name that HOMOLOGUE! Structure: UroGenital sinus M-Urethra F?

A

Urethra & Lower Vagina

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9
Q

Name that HOMOLOGUE! Structure:Wolffian Duct M-Rete testis F?

A

Rete ovarii

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10
Q

What are the 4 structures that develop from the Wolffian Duct in the male?

A

1.Rete Testis 2.Epididymis 3.Vas Deferens 4.Seminal Vesicles

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11
Q

Name that HOMOLOGUE! Structure: Mullarian duct F-Fallopian tubes M?

A

Appendix Testis

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12
Q

What are the 3 structures that develop from the Mullerian Duct in the Female?

A

1.Fallopian Tubes 2.Uterus 3.Upper Vagina

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13
Q

Although the sex is determined genetically at the point of fertilization, the gonads do not acquire male or female characteristics until the _______ week of development.

A

7th week

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14
Q

What does it mean if the SRY gene is present?

A

testis/ male development is established

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15
Q

What happens if the SRY gene is absent?

A

Female development established

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16
Q

What is the street name for the Mesonephric duct? Which sex is this going to develop in?

A

Mesonephric Duct = Wolffian Duct…Males

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17
Q

What is the street name for the paramesonephric duct which gender does this develop in?

A

Para-meso-nephric duct = Mullerian duct…Females

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18
Q

What are the structures that develop from the para-meso-nephric ducts?

A

1.Fallopian Tube Fimbria 2.Uterine canal (3.uterus 4.cervix and 5. vagina)

19
Q

What structure arises from the posterior UroGenital Sinus? What 2 structures arise from the anterior Urogenital Sinus?

A

Posterior UG sinus-Lower Vagina…..Anterior UG sinus- urinary bladder & urethra

20
Q

Contact of the urogenital sinus by the paramesonephric ducts induces formation of the _________.

A

sinovaginal bulbs

21
Q

Describe the migration of the primitive germ cells.. 1st part of 3…..The primitive germ cells begin as _______/______ cells in the wall of the _______ near the ________ and migrate along the mesentery of the _______.

A

MESENCHYMAL/STEM….YOLK SAC….ALLANTOIS….HINDGUT

22
Q

Describe the migration of the primitive germ cells.. Part 2 of 3: The primordial germ cells continue migration until they reach the _________ and penetrate into the primitive gonad by the _____ week.

A

gonadal ridges…6th week

23
Q

Describe the migration of primitive germ cells (Part 3 of 3) What they INSERT into!.. Before and during the arrival of the primordial germ cells, the overlying epithelium of the __________ proliferates and penetrates the underlying mesenchyme forming a number of ___________. Some of the primordial germ cells are surrounded by cells of the primitive sex cords.

A

genital ridge……primitive sex cords

24
Q

What structure develops from the production of the UG sinus and then the canalization of the UG sinus? (internal and external structures) DESCRIBE IN 3 STEPS

A
  1. Sinovaginal Bulb —-> 2.Forms a column of tissue 3.Canalizes to form the upper 2/3 of the Vagina to the Hyman.
25
Q

The lower part of the vagina is formed from the?

A

posterior wall of the urogenital sinus

26
Q

The _________ is a collection of endoderm from the wall of the UroGenital Sinus.

A

SinoVaginal Bulbs

27
Q

What is DES? Why was it given?

A

Di-Ethyl-Stil-best-eril (DES) ‘morning after pill’- 1940’s 50’s to keep a pregnancy going

28
Q

What does DES cause?

A

Vaginal Adenosis and increased risk to Clear Cell AdenoCarcinoma

29
Q

What condition refers to failure of the normal glandular epithelium that lines the embryonic vagina to be replaced by squamous epithelium during fetal development?

A

Vaginal Adenosis caused by DiEthylStilbesteril (DES)

30
Q

What condition manifests grossly as red, granular patches on the vaginal mucosa which usually disappear as the woman gets older.

A

Vaginal Adenosis (DES caused)

31
Q

In Vaginal Adenosis: microscopically, there is mucinous ________, similar to the endocervix, along with ciliated cells with eosinophilic cytoplasm, similar to the lining cells of the fallopian tube and endometrium…The glandular cells ultimately undergo squamous ________.

A

columnar cells……metaplasia

32
Q

Where does Clear cell Adneocarcinoma due to DES most frequently develop?

A

the Anterior wall of the upper 1/3 of the Vagina

33
Q

What are the 3 manifestations of an imperforate hymen in the newborn? What color is the membrane most likely to be?

A
  1. Mucocolpos-bulging hymenal membrane between the labia (WHITE membrane)…2.UTI 3.Bladder Obsrtuction
34
Q

What are the 3 complications of an imperforate hymen in an adolescent female?

A

1.HematoMetroColpos (menses backed up in uterus) 2.HematoSalpinx (reflux of menses to fallopiantubes) 3.Pyocolpos (infected material invaginal cavity-causing ascending genital tract infections

35
Q

What are the 3 clinical manifestations of an imperforate hymen in an adolescent female? What color is associated with this?

A
  1. Amenorrhea 2.Lower ab/pelvic pain 3.Urinary retention/constapation…Bluish hymenal membrane (c/o collected menstrual blood) (hematocolpos)
36
Q

What is the possible result of an imperforate hymen causing hematosalpinx?

A

Secondary Endometriosis

37
Q

Histologically, what is vaginal adenosis and why do we get it? What does DES do again?

A

The glandular tissue does not get replaced by squamous epithelium! DES arrests this process!

38
Q

What part of the female genital tract would you expect to find fimbriae?

A

The Fallopian Tubes!

39
Q

What part of the female genital tract would you expect to find the vestibule?

A

The vulva!

40
Q

What part of the female genital tract would you expect to find Bartholin’s glands?

A

The vulva!

41
Q

What part of the female genital tract would you expect to find Rugae?

A

The vagina!

42
Q

What part of the female genital tract would you expect to find the corpus luteum?

A

the ovaries!

43
Q

What part of the female genital tract would you expect to find the tunica albuginea?

A

the ovaries!

44
Q

What do the primitive sex cords develop into in the female reproductive tract? What do they become by the 4th month?

A

Cell clusters in the Outer, active surface epithelium…they surround the primitive germ cells (oogonia) and form FOLLICULAR cells

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