Repro Endocrinology Flashcards
All hormone receptors are __
proteins
Progesterone, estrogen and testosterone are all __ based and have a __ charge
cholesterol, neutral
Steroid hormone receptors are located in the __
nucleus
FSH + LH bind to follicle cells in the ovary which results in synthesis of a new product __
Estradiol
GNRH source, target tissue and primary action in females
source: hypothalamic surge and tonic centers
Target tissue: anterior pituitary
Primary action: release FSH + LH
LH source, target tissue and primary action in females
Source: anterior pituitary
Target tissue: ovary (theta internal + luteal cells)
Primary Action: stimulates ovulation, form corpora lutea + progesterone secretion
FSH source, target tissue and primary action in females
Source: anterior pituitary
Target tissue: ovary (granulosa cells)
Primary action: follicular development + estradiol synthesis
GNRH source, target tissue and primary action in males
Source: hypothalamic surge and tonic centers
Target tissue: anterior pituitary
Primary action: release FSH and LH
LH source, target tissue, and primary action in males
Source: anterior pituitary
Target tissue: testis
Primary action: stimulate testosterone production
FSH source, target tissue, primary action for males
source: anterior pituitary
Target tissue: testis (serotonin cells)
Primary action: Sertoli cell function
Hypothalamic- pituitary- gonadal - axis
primary reproductive regulatory system for puberty, seasonality, cyclicity
Gonadotrophin Releasing Hormone travels locally to the pituitary via a __ while it travels systemically to the gonads via __
portal vein, general circulation
FSH and LH are both __
gonadotropins
gonadal hormones of the testis including leydig cells secrete __ while sertoli cells secrete __
testosterone, inhibin
leydig cells -> testosterone -> anterior pituitary = __
suppress FSH
