Repro 1

Question 1

Role of aromatase

Answer 1

Converts testosterone to estradiol

Question 2

Role of 5α-reductase

Answer 2

Converts testosterone to DHT

Question 3

Hierarchy of determinants of sexual differentiation

Answer 3

Genetic sex → Gonadal sex → Genital sex → Gender sex

Question 4

Aneuploidy, Mosaicism, Chimerism, Structural Errors

XO (Turner’s)
XXY (Klinefelter’s - seminiferous tubule dysgenesis)

Answer 4

Genetic sex abnormalities

Question 5

Gonadal dysgenesis

Answer 5

Gonadal sex abnormalities

Question 6

Congenital adrenal hyperplasia (21α-hydroxylase deficiency)

Answer 6

Genital sex abnormalities

Question 7

Prostate development (DHT, T, or E2)

Answer 7

DHT

Question 8

Beard growth (DHT, T, or E2)

Answer 8

DHT

Question 9

Sebum formation (DHT, T, or E2)

Answer 9

DHT

Question 10

Pubertal development - penis, seminal vesicles (DHT, T, or E2)

Answer 10

DHT and T

Question 11

Sperm production (DHT, T, or E2)

Answer 11

DHT, T, and E2

Question 12

Liver development (increase VLDL, LDL; reduce HDL)

Answer 12

Testosterone

Question 13

RBCs (DHT, T, or E2)

Answer 13

T

Question 14

Muscle mass (DHT, T, or E2)

Answer 14

T

Question 15

Abdominal visceral fat (DHT, T, or E2)

Answer 15

T

Question 16

Skeleton (DHT, T, or E2)

Answer 16

T and E2

Question 17

Larynx (male voice) (DHT, T, or E2)

Answer 17

T

Question 18

Imprint male pattern of gonadotropins, sex drive, behavior (DHT, T, or E2)

Answer 18

DHT, T, and E2

Question 19

Feedback suppression of gonadotropin secretion (DHT, T, or E2)

Answer 19

DHT, T, and E2

Question 20

Epididymis (DHT, T, or E2)

Answer 20

T

Question 21

Vas deferens (DHT, T, or E2)

Answer 21

T

Question 22

Seminal vesicles (DHT, T, or E2)

Answer 22

T

Question 23

Intrauterine differentiation - penis, scrotum, urethra, prostate

Answer 23

DHT