Adolescence and Puberty Conference

Question 1

Abnormal difference in Tanner stages

Answer 1

> 2 stages

Question 2

First signs of male pubertal development

Answer 2

Testes enlargement (3-4 mL volume)

Question 3

First signs of female pubertal development

Answer 3

Breast buds

↑ estrogen, ovarian growth

Question 4

Normal menstrual cycles depend on ________ feedback

Answer 4

Positive feedback

Question 5

Upper age limit for normal pubertal development: females

Answer 5

Menses by 13 y/o

Question 6

Order of puberty (female)

Answer 6

thelarche → adrenarche → PHV → menarche

breast development → androgen effects (pubic hair ) → peak height velocity → periods

Question 7

Normal age for first menses

Answer 7

11 - 14 y/o (avg = 12.5)

Question 8

Hormone secreted by the hypothalamus

Answer 8

GnRH

- responsible for the release of LH and FSH from the anterior pituitary

Question 9

Hormones secreted by the anterior pituitary

Answer 9

FSH, LH (gonadotropins)

Question 10

FSH stimulates ___________

Answer 10

Female: granulosa (produces sex steroids. FSH converts androgens to estradiol during follicular phase of menstrual cycle)
Male: Sertoli cells (“support” cells. Helps with spermatogenesis)

Question 11

LH stimulates ___________

Answer 11

Female: theca
Male: Leydig cells

role: secretion of androgens

Question 12

First signs of male pubertal development

Answer 12

Testes enlargement (3-4 mL volume)

Question 13

First signs of female pubertal development

Answer 13

Breast buds

↑ estrogen, ovarian growth

Question 14

Precocious puberty: males

Answer 14

before age 9

Question 15

Precocious puberty: females

Answer 15

before age 6 (white)

before age 5 (black)

Question 16

Normal menstrual cycles depend on ________ feedback

Answer 16

Positive feedback

Question 17

Upper age limit for normal pubertal development: females

Answer 17

Menses by 13 y/o

Question 18

Order of puberty

Answer 18

Thelarche → menarche

Question 19

Normal age for first menses

Answer 19

11 - 14 y/o (avg = 12.5)

Question 20

Hormone secreted by the hypothalamus

Answer 20

GnRH

- responsible for the release of LH and FSH from the anterior pituitary

Question 21

Hormones secreted by the anterior pituitary

Answer 21

FSH, LH (gonadotropins)

Question 22

FSH stimulates ___________

Answer 22

Female: granulosa (produces sex steroids. FSH converts androgens to estradiol during follicular phase of menstrual cycle)
Male: Sertoli cells (“support” cells. Helps with spermatogenesis)

Question 23

LH stimulates ___________

Answer 23

Female: theca
Male: Leydig cells

role: secretion of androgens

Question 24

Common adrenal hyperplasia (CAH) is a deficiency of these

Answer 24

Either 11- or 21-hydroxlyase, leading to an increase in production of 17-OH steroids (androgens)