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Renal Medicine > Renal Tubular Acidosis > Flashcards

Renal Tubular Acidosis Flashcards

1
Q

What is renal tubular acidosis?

A

Metabolic acidosis due to tubule pathology

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2
Q

How many types of renal tubular acidosis are there?

A

4

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3
Q

What is type 1 renal tubular acidosis?

A

Distal tubule pathology -> unable to secrete H+ ions

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4
Q

What causes type 1 renal tubular acidosis?

A 
Genetic 
SLE
Sjogrens
PBC
Hyperthyroidism
Sickle cell anaemia
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5
Q

What are features of type 1 renal tubular acidosis?

A 
Failure to thrive
Hyperventilation occur
CKD
Low potassium
High urine pH
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6
Q

Why does hyperventilation occur in type 1 renal tubular acidosis?

A

To compensate for metabolic acidosis

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7
Q

How is type 1 renal tubular acidosis managed?

A

Oral bicarbonate

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8
Q

What is type 2 renal tubular acidosis?

A

Proximal tubule pathology -> unable to reabsorb bicarbonate

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9
Q

How is type 2 renal tubular acidosis managed?

A

Oral bicarbonate

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10
Q

What is type 3 renal tubular acidosis?

A

Combination of type 1 & 2

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11
Q

What is type 4 renal tubular acidosis?

A

Reduced aldosterone

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12
Q

What can cause type 4 renal tubular acidosis?

A 
Adrenal insufficiency 
ACEi
Spironolactone
SLE
HIV
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13
Q

What are features of type 4 renal tubular acidosis?

A

Raised potassium
Raised chloride
Low urine pH

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14
Q

How is type 4 renal tubular acidosis managed?

A

Fludrocortisone

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Renal Medicine (13 decks)

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