Renal System Flashcards

1
Q

What is the function of the kidneys?

A

Filter, Reabsorption, Endocrine, Excretion, Fluid & Electrolyte Imbalance, pH control, & detoxification of free radicals
(FREE DEFP)

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2
Q

Where does the nitrogen in urea come from?

A

Breakdown of DNA & RNA

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3
Q

What is BUN?

A

Blood Urine Nitrogen

- Measure of nitrogen waste in blood (measure of kidney function)

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4
Q

What is the BUN?

A

7-18 mg/dl

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5
Q

What are the creatine levels?

A

.7-1.2 mg/dl

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6
Q

Where does creatine come from?

A

Breakdown of creatine phosphate

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7
Q

What is the function of creatine phosphate?

A

transfers phosphate to ADP to form ATP

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8
Q

What enzyme is associated with creatine phosphate?

A

Creatine kinase

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9
Q

How much protein is in urine?

A

Only .03% (should be very little protein in urine)

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10
Q

How much fluid does a kidney filter per day?

A

180L

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11
Q

How much fluid is reabsorbed?

A

99.3%

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12
Q

What hormones/vitamins are found with kidneys

A

Erythropoietin, Vitamin D3, & renin

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13
Q

What is the function of vitamin D3?

A

Increases intestinal absorption of CA++ & PO4-3 for building bones

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14
Q

How does the kidneys have pH control?

A

Buffers the blood

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15
Q

What is retroperitoneal?

A

The kidneys (behind the peritoenum)

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16
Q

How many nephrons in a kidney?

A

1 million

17
Q

What are the 2 levels of mechanical filtration?

A

Fenestrae & podocytes

18
Q

Describe fenestrae

A

Windows/holes in glomerular capillaries

19
Q

Describe basement membrane

A

Has (-) charge

- This repels proteins that are smaller than the opening of the fnestrae & podocytes

20
Q

Describe podocytes

A

Cells that cover glomerular capillaries & has filtration slits

21
Q

What are the two types of nephrons?

A

Cortical & Juxtamedullary

22
Q

Describe the cortical nephrons

A

Corpuscle is more superficial & loop of henle is not as deep into the medulla

23
Q

Describe juxtamedullary nephron

A

Corpuscles are depper & loop of henle is deep in medulla

24
Q

What is the afferent arteriole?

A

Brings unfiltered (dirty) blood to corpuscle

25
Q

Describe the efferent arteriole

A

Takes cleaned blood back to circulatory system

26
Q

What are the 4 structures in a renal corpuscle?

A

Bowman’s capsule, bowman’s space, glomerular capillaries & podocytes

27
Q

Describe the bowman’s capsule

A

Outer shell, made of simple squamous epithelium

28
Q

Describe the bowman’s space

A

Collects filtrate

29
Q

Describe glomerular capillaries

A

Filters capillaries with fenestrae

30
Q

Describe podocytes

A

Cells cover glomerular capillaries with filtration slits (looks like a bunch of Patrick Stars)

31
Q

What is the function of the proximal convoluted tubles

A

Takes filtrate from corpuscle

32
Q

How much in the PCT is water reabsorbed?

A

65%

33
Q

How much water reabsorption is done in the loop of henle?

A

15%

34
Q

What happens in the thick descending limb of the loop of henle?

A

Water leaves (concentrating limb)

35
Q

What happens in the thick ascending limb of the loop of henle?

A

Salt leaves, but not water (diluting limb)

36
Q

How much water reabsorption in DCT?

A

10%