Renal and Metabolic Diseases Flashcards
4 types of kidney disease
Glomerular
Tubular
Interstitial
Vascular
[GTIV]
Clinical presentation of glomerular disease
Nephritic and Nephrotic syndrome
Disruption of the foltration barrier due to the damage og the membrane and changes in electrical charges
Nephrotic syndrome
Deposition of immune complexes formed in conjunction with Grp A streptococcus infxn
Acute Poststreptococcal Glomerulonephritis
Deposition of immune complexes from systemicc immune disorder on the glomerular membrane
Rapid Progressive (crescentic) glomerulonephritis
Attachment of cytotoxic Ab formed during viral respiratory infxn
Goodpasture Sundrome
Initial pulmonary complaints in Goodpasture syndrome
Hemoptysis and dyspnea
Positive result of Goodpasture syndrome
Anti-glomerular basement membrane Ab
Antineutrophilic cytoplasmic auto-Ab bind to neutrophil in vascular walls
Wegener’s granulomatosis
Positive results of Wegener’s Granulomatosis
Antineutrophilic cytoplasmic auto-Ab (ANCA)
Thickening of the glomerular membrane following IgG immune complexes
Membranous Glomerulonephritis
Cellular proliferation affecting the capillary walls
Membranoproliferative glomerulonephritis
Deposition of IgA resulting from increased level of serum IgA
IgA nephropathy
IgA nephropathy is also known as
Berger disease
It is considered to be the MOST COMMON Glomerulonephritis
Bergers disease/ IgA nephropathy