Renal Flashcards

1
Q

What % of CRF have renal hypertension in dogs and cats, respectively?

A

Dogs: 60%
Cats: 21%

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2
Q

Afferent dilation increases/decreases GFR

Efferent dilation increases/decreases GFR

A

Afferent dilation increases GFR

Efferent dilation decreases GFR

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3
Q

MOA of ADH

A

Vasopressin 2 (V2) receptors –> camp/PKA and aquaporin 2 insertion into luminal membrane

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4
Q

Nephritic syndrome

A

Glomerular leakage large enough to allow passage of RBCs

Seen hematuria and RBC casts

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5
Q

Somatic control of urethral sphincter

A

Pudendal nerve
Sympathetic control –> hypogastric nerve
Parasympathetic control –> pelvic nerve

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6
Q
Urine dipstick false in results
Elevated USG:
Elevated pH:
Glucose false +:
Blood false +:
Bilirubin false +:
Ketones false +:
A

Urine dipstick false in results
Elevated USG: protein, glucose
Elevated pH: glucose
Glucose false +: bleach, peroxide, antibiotic
Blood false +: bleach, iodide/bromide or microbial peroxidase
Bilirubin false +: chlorpromazine or NSAIDs
Ketones false +: pigmenturia

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7
Q

Where is Mg absorbed in tubule?

A

Thick ascending LOH (60%)

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8
Q

Where the most Na is absorbed in tubule?

A

Proximal convulted tubule (PCT) = 65%

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9
Q

Where the most H2O is absorbed in tubule?

A

Proximal convulted tubule (PCT) = 65%

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10
Q

Where the most glucose is absorbed in tubule?

A

Proximal convulted tubule (PCT) = 100%

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11
Q

Where the second most H2O is absorbed in tubule?

A

Thin descending LOH = 20%

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12
Q

Where the second most Na is absorbed in tubule?

A

Thick ascending LOH = 25%

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13
Q

Where the most Phosphorus is absorbed in tubule?

A

Proximal convulted tubule (PCT) = 85%

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14
Q

What urinary stone does Dalmatians who are on allopurinol?

A

Xanthine stones

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15
Q
IRIS staging; cutoff creatinine value
Stag I 
Stag II 
Stag III 
Stag IV
A
IRIS staging; cutoff creatinine value
Stag I: Dogs < 1.4, Cats < 1.6
Stag II: Dogs 1.4-2.0, Cats 1.6-2.8
Stag III: Dogs 2.1-5.0, Cats 2.9-5.0 
Stag IV: Dogs > 5.0, Cats > 5.0
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16
Q

Which lesion does gentamicin damage in the kidney?

A

Proimal tubule

17
Q

Where is ADH secreted?

A

Synthesized supraoptic nucleus in thalamus, and secreted from posterior pituitary.