GI Flashcards
Where does somatostatin come from? (2 organs)
Pancreatic delta cells
anterior pituitary gland
What organ secretes gastrin normally (in adult life)?
What organ secretes gastrin in fetal life?
Normally - G cells in stomach/pyloric antrum in adult life
Fetal life - pancreatic beta cells
GI hormone responsible for protein breakdown in stomach?
pepsin
Pancreatic enzyme secretion (2)?
secretin & CCK
Glucagon is inhibited by ___, ___, ___, ___.
Insuline, somatostatin, secretin, motilin
Nutrients absorbed in the ileum
cobalamin, bile acids
DKA hormones
Increased HSL
Decreased LPL
What is alpha 1 proteinase inhibitor as a marker for?
PLE
It presents in vascular and interstitial spaces
Lost intestinal tract with PLE and excreted intact
What does chief cells in the stomach secrete?
pepsinogen
Also mucus cells secrete pepsinogen along with mucus
What is the characterizations regarding Basenji’s enteritis?
Immunoproliferative enteropathy
Hereditary form of PLE
Severe hypoalbuminemia and hyperglobulinemia due to high IgA production (distinctly different from IBD)
May be predisposed to LSA
SI lesions: increased CD4+ and CD8+ T cells
What is the primary intracellular protective molecules which helps prevent pancreatic auto-digestion?
Pancreatic secretory trypsin inhibitor
What is Leptin?
It is increased in obesity, CKD patients
Maintains satiety
