Miscellaneous

Question 1

Dog shock organ

Answer 1

GI

Question 2

Cat shock organ

Answer 2

Lungs

Question 3

What is the precursor of serotonin (5HT)?

Answer 3

Tryptophan

Question 4

Total body water distribution

• Water = ___ % of body
• Intracellular = ___ %
• Extracellular = ___ %
  
  • Interstitial = ___ %
  • Plasma = ___ %

Answer 4

• Water = 60% of body
• Intracellular = 40%
• Extracellular = 20 %
  
  • Interstitial = 15%
  • Plasma = 5%

Question 5

Osmolality =

Answer 5

Osmolality = 2Na + (Glucose/18) + (BUN/2.8)

• BUN, glue are ineffective osmoles
• Alb is the most potent determinant of oncotic force

Question 6

What IVF is a hyperosmolar with lower oncotic pressure?

Answer 6

7.5% NaCl

Question 7

What IVF is an isotonic crystalloid?

Answer 7

D5W

Question 8

What IVF is a higher oncotic pressure but isotonic?

Answer 8

Dextrans

Question 9

What IVF is a higher oncotic pressure and hypertonic?

Answer 9

Hetastarch

Question 10

Which organ is PTHrP NOT normally found in?

Answer 10

Kidney

Question 11

Examples of organs PTHrP is present normally

Answer 11

Bone, mammary gland, skin

Question 12

What is cohort study?

Answer 12

A study of a group with a specific characteristic or experience.

Question 13

What is cross sectional study?

Answer 13

A study of many subjects at the same point in time.

Question 14

Which administration method is the most susceptible to first pass metabolism? How we can avoid it?

Answer 14

Most susceptible: oral

Can be avoided by transmucosal or rectal administration

Question 15

What AUC means?

Answer 15

The % of a drug that reaches systemic circulation

If AUC of both curves is equal, bioavailability is 100%.