Renal Flashcards

0
Q

What is Goldblatt’s kidey?

A

Flea bitten kidney ( blown capillaries)

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1
Q

Which part of the nephron concentrates urine?

A

Medulla

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2
Q

What is uremia?

A

Azotemia + symptoms

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3
Q

What is azotemia?

A

Increased BUN/Cr

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4
Q

What is nephritic kidney disease?

A

Increased size of fenestrations => vascilitis

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5
Q

What is nephrotic kidney disease?

A

Lost of BM charge due to deposition of heparin sulphate => massive proteinuria and lipiduria

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6
Q

What is seen in RPGN?

A

Crescents

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7
Q

What is post-strep GN?

A

Subepithelial IgG, C3, C4 deposition. Also Ab.

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8
Q

What is interstitial nephritis?

A

Urine eosinophils

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9
Q

What is lupus nephritis?

A

Subepithelial

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10
Q

What is MGN?

A

Deposition

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11
Q

What is MPGN?

A

Tram track appearance ( type II has C3)

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12
Q

What is. Minina Change Disease?

A

Kids, fused foot proscesses, no renal failure, loss of charge barrier

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13
Q

Whats is FSGN?

A

AA, HIV pts.

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14
Q

What are the vasculitis w/ low C3?

A
PMS in Salt Lake City
Poststrep GN
MPGN Type II
SBE
Serum sickness
Lupus
Cryoglobulinemia
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15
Q

What are the most common cause of kidney stones?

A

Dehydration

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16
Q

What are the most common types of kidney stones?

A

Calcium pyrophosphate

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17
Q

What type of kidney stones have coffin lid appearance?

A

Triple phosphate

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18
Q

What type of kidney stones have hexagonal crystals?

A

Cystine

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19
Q

What type of kidney stone have envelope or dumbell shape?

A

Oxalate

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20
Q

What disease has aniridia?

A

Wilm’s tumor

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21
Q

What disease has iridiocyclitis?

A

Juvenile rheumatic arthritis

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22
Q

What is phimosis?

A

Foreskin scarred at the penis head ( ventral part)

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23
Q

What is paraphimosis?

A

Forerskin of the penis scarred a the base (retraction of foreskin=> strangulate penis)

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24
What is urge incontinence?
Urgency leads to complete voiding (detrussor spasticity=>small bladder vol)
25
What is stress incontinence?
Weak oelvic floor muscles (estrogen effect)
26
What is overflow incontinence?
Runs down the leg but can't completely empty bladder
27
What structures have a one way valve?
Urethra, ejaculatory duct
28
What structures have fake sphincters?
Ureters, LES, ileocecal valve
29
What has WBC casts?
Nephritis
30
What has WBC casts only?
Pyelonephritis (sepsis)
31
What has WBC casts + eosinphils?
Interstitial nephritis (allergies)
32
What has WBC casts + RBC casts?
Glomerulonephritis
33
What has fat casts?
Nephrotic syndrome
34
What has waxy casts?
Chronic renal failure
35
What has tubular casts?
ATN
36
What has muddy brown casts?
ATN
37
What has hyline casts?
Normal sloughing
38
What has epithelial casts?
Normal sloughing
39
What has crescents?
RPGN (goodpasture, Wegener's)
40
How do you measure afferent renal function?
Creatinine or Inulin
41
How do measure efferent renal function?
BUN or PAH
42
What is the afferent arteriole's job?
Filter
43
What is the efferent arteriole's job?
Secrete
44
How do you test afferent arteriole function?
GFR
45
How do you test efferent arteriole function?
RPF
46
What is pre renal failure?
Low flow to the kidney (BUN:Cr >20)
47
What is the job of the proximal tubule?
Reabsorb Glucose, amino acids, salts, bicarb
48
What is the job of the thin ascending limb?
Reabsorbs water
49
What is the job of the thick ascending limb?
Make the concentration gradient by reabsorbing Na, K, Cl, Mg, Ca, without water
50
What is the job of the early distal tubule?
Cancentate urine by reabsorbing NaCl (hypotonic)
51
What is the job of the late distal tubule?
Final concentation of urine by reabsorbing water, excretion of acid (isotonic)
52
What does the macula densa do?
Measure osmolarity
53
What does the JG apparatus do?
Measures volume
54
What is Fanconi syndrome?
Old tetracycline use, urine phosphate, glucose, amino acids
55
What is Bartter's syndrome?
Baby w/ defective triple transporter (low Na, Cl, K, w/ normal BP)
56
What is psychogenic polydipsia?
No concentrating ability=> cerebral edema
57
What is hepatorenal sydrome?
High urea from liver => increase glutaminase=>NH4 =>GABA=>kidney stops working
58
What is type I RTA?
Distal renal tubule acidosis: H/K in CD is broken=>high urine pH (UTI, stones, Li)
59
What is type II RTA?
Proximal RTA: bad CA=> lose all the bicarb=> low urine pH (multiple myeloma)
60
What is type 3 RTA?
RTA I + II=> normal urine pH (5-6)
61
What is type 4 RTA?
Infarct JG=> no renin=> no Aldo=>high K=> DM, NSAIDS, ACE-I, heparin)
62
What is central pontine myelinosis?
Due to correctin Na faster than 0.5 mEq/hr.