Renal (10-11) Flashcards

1
Q

How does the GFR change with age?

A

Decreases -partly due to reduction in number of nephrons

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2
Q

How does GFR in fetal life compare to that of the adult?

A

Low- homeostatic functions performed by the placenta

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3
Q

What are the two types of nephrons in birds?

A

Reptilian -type nephron ( no loop of Henule)

Mammalian-type nephrons (with loops of Henle)

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4
Q

How can birds regulate osmolaity after the kidney?

A

Altered in the cloaca

Antiperistaltic contractions move cloaca content to intestine

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5
Q

What additional way can birds regulate salt balance

A

Salt glands

Birds that drink sea water

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6
Q

In what form is nitrogen excreted in birds?

A

Uric acid

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7
Q

Under normal conditions our kidneys produce (hypotonic /hypertonic) urine

A

Hypertonic

Produce concentrated urine

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8
Q

If there is a high water load in the body, will the kidney produce hyper or hypotonic urine?

A

Hypotonic

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9
Q

Where does water reabsorption NOT occur in the nephron?

A

Ascending limb

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10
Q

What is the pressure in the peritubular capillaries compared to the glomerular capillaries?

A

More oncotic pressure
Pull water in from the interstitial fluid that is reabsorbed in the PT

Very low hydrostatic pressure in peritubular capillaries

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11
Q

The medullary intersitium is hyper-/iso-/hypo-tonic to the tubule lumen??

A

Hypertonic

The high concentration of the interstitium draws water out of the nephron lumen

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12
Q

What is required form formation of concentrated urine?

A

Hypertonic medullary interstitium
High water permeability in thin descending limb and collecting ducts
Reabsorption of water by vasa recta

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13
Q

What are the three main solutes responsible for the hypertonicity of the medulla?

A

Na+, Cl-, and urea

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14
Q

In the descending thin limb ______ is reabsorbed, which (increase/decrease) the osmolaity of the tubular fluid

A

Water

Increases

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15
Q

In the thin ascending limb, ______ is reabsorbed

A

NaCl

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16
Q

The thick ascending limb is impermeable to ______ but reabsorbs ________
Which (increases or decreases) osmolaity of medullary interstitium

A

water
NaCl
Increases

17
Q

What two things maintain the medullary hypertonicity?

A

Active NaCl in thick ascending limb

Urea reabsorption in collecting duct

18
Q

Reabsorption of ________ in the collecting duct increases the osmolality of the interstitum

A

Urea

19
Q

fluid flow in opposite directions allowing for maximal exchange of solute/heat/water

A

Countercurrent exchange

20
Q

How does the the vasa recta reabsorb water from the interstitium ?

A

?????