Relationship Testing Flashcards

1
Q

Described the charged polymorphism of haptoglobin

A

1955 Smithies

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2
Q

Demonstrate that the ABO blood group frequency distribution in Austria

A

Bernstein 1924

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3
Q

We’re officially recognize by the FBI as the core loci to be used to create query the database of convicted offender

A

13core STR loci plus amelogenin

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4
Q

Amelogenin are used by the FBI for

A

Sex determination

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5
Q

A group of genetic system wherein the detection of the polymorphisms where all dependent on a complex biochemical expression of the original gene

A

Classic system

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6
Q

Refers to polymorphisms in DNA that can be revealed by restriction enzyme digestion because of nucleotide sequence differences that either create or destroy restriction sites

A

Restricted fragment length polymorphisms

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7
Q

Classic genetic systems use in parentage testing

A

RBC antigen
RBC enzyme and serum proteins
Immunoglobulin Allotypes
HLA

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8
Q

Are defined as the length of DNA fragments in kilobases estimated through comparison to a sizing ladder consisting of DNA fragments of known size

A

Phenotype

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9
Q

Indirect exclusion is also referred as ?

A

Apparent opposite homozygosity

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10
Q

The limit of resolution is referred to as

A

Delta

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11
Q

In DNA: RFLP variability is referred as

A

Sigma

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12
Q

The range of matching allele sizes is called

A

bin

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13
Q

2 Most common restricted enzyme used in USA

A

Hae III and Pst I

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14
Q

Restricted enzyme use in Europe

A

Hint I

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15
Q

Name of the bacteria wherein Hae III enzyme is restricted

A

Haemophilus aegyptus

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16
Q

Paternity index is also known as

A

System index

17
Q

Compares two mutually exclusive hypothesis that are expressed as a likelihood ratio

A

Paternity index

18
Q

Is the probability of excluding a false,y accused man giving the phenotype of the mother and child

A

Probability exclusion

19
Q

Is a restatement of the weight of the evidence for parentage expressed in parentage form

A

Probability paternity

20
Q

Give the formula probability paternity

A

( [PI) ( prior for ) ] / [ ( PI ) ( prior for ) + prior against

21
Q

Refers to the testing of genetic markers that are inherited to confirm or refute a biological relationship

A

Relationship testing or parentage testing

22
Q

Classic Genitic System Used in Parentage Testing using RBC Enzymes and Serum Proteins

A

H-E-P-A - G