Relationship Testing Flashcards
Described the charged polymorphism of haptoglobin
1955 Smithies
Demonstrate that the ABO blood group frequency distribution in Austria
Bernstein 1924
We’re officially recognize by the FBI as the core loci to be used to create query the database of convicted offender
13core STR loci plus amelogenin
Amelogenin are used by the FBI for
Sex determination
A group of genetic system wherein the detection of the polymorphisms where all dependent on a complex biochemical expression of the original gene
Classic system
Refers to polymorphisms in DNA that can be revealed by restriction enzyme digestion because of nucleotide sequence differences that either create or destroy restriction sites
Restricted fragment length polymorphisms
Classic genetic systems use in parentage testing
RBC antigen
RBC enzyme and serum proteins
Immunoglobulin Allotypes
HLA
Are defined as the length of DNA fragments in kilobases estimated through comparison to a sizing ladder consisting of DNA fragments of known size
Phenotype
Indirect exclusion is also referred as ?
Apparent opposite homozygosity
The limit of resolution is referred to as
Delta
In DNA: RFLP variability is referred as
Sigma
The range of matching allele sizes is called
bin
2 Most common restricted enzyme used in USA
Hae III and Pst I
Restricted enzyme use in Europe
Hint I
Name of the bacteria wherein Hae III enzyme is restricted
Haemophilus aegyptus
Paternity index is also known as
System index
Compares two mutually exclusive hypothesis that are expressed as a likelihood ratio
Paternity index
Is the probability of excluding a false,y accused man giving the phenotype of the mother and child
Probability exclusion
Is a restatement of the weight of the evidence for parentage expressed in parentage form
Probability paternity
Give the formula probability paternity
( [PI) ( prior for ) ] / [ ( PI ) ( prior for ) + prior against
Refers to the testing of genetic markers that are inherited to confirm or refute a biological relationship
Relationship testing or parentage testing
Classic Genitic System Used in Parentage Testing using RBC Enzymes and Serum Proteins
H-E-P-A - G