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Fundamentals in Blood Bank > Blood Components and Deriviatives > Flashcards

Blood Components and Deriviatives Flashcards

1
Q

2 Fxn of Whole Blood

A

Replacement of O2 carrying capacity

Maintainance of Intravascular Vol.

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2
Q

Fxn of Packed Red Blood Cell

A

To increase O2 carrying capacity of blood in patient with Acute Chronic Anemia who are symptomatic or at High risk for end organ damage

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3
Q

Volume of Packed Red Blood Cell

A

260 ml

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4
Q

A product in which all of the red cells and most of the plasma from the original unit remain

A

Whole blood

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5
Q

Volume of Whole Blood

A

540 ml

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6
Q

Packed RBC maybe prepared from whole blood by _______ or by ________

A

Overnight sedimentation or by Centrifugation using Heavy Spin

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7
Q

Whole Blood Shell life for CPA-1

A

35 Days at 1-6*C

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8
Q

Whole Blood Shell life for CPD

A

21 Days at 1-6*C

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9
Q

In packed RBC what are the two symptoms of Acute Chronic Anemia mentioned

A

Syncope and Dyspnea

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10
Q

Give example in Packed RBC for High Risk for end organ damage

A

Subcritical Coronary Atherosclerosis

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11
Q

How many ml of Additive solution is added in the RBC

A

100ml

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12
Q

Volume of RBC added with Additive solution

A

340ml

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13
Q

3 Fxn/Uses of transfused Washed RBC

A
  1. Prevention of recurrent or severe allergic reactions
  2. Neonatal intrauterine transfusion
  3. Prevention of anaphylactic reaction in IgA deficient patients
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14
Q

Washed RBC volume

A

180ml

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15
Q

Wahsed RBC Shelf Life

A

24hrs at 1-6*C

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16
Q

3 Fxn/Uses of Frozen Deglyceralyzed RBC

A
  1. Long Term preservation of RBC units with rare phenotype or autologous RBC units
  2. Alternative to CMV seronegative unit emergencies
  3. Decrease febrile transfusion reaction
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17
Q

Removes >90% of WBC

A

Frozen Deglyceralized RBC

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18
Q

Shelf life of Frozen Deglyceralized RBC

A

10 years at -65 to - 200 *C

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19
Q

Shelf life of Frozen Deglyceralized RBC after washing

A

24 hrs at 1-6*C

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20
Q

Volume of Frozen Deglyceralized RBC

A

250ml

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21
Q

4 Fxn/uses Leukocyte Reduced RBC

A
  1. Decreased the risk of alloimmunization to HLA antigens on leukocyte
  2. Decrease Febrile Non-Hemolytic transfusion reaction
  3. Reduce the risk of CMV infection
  4. Decrease immunomodulation and may decrease the risk of prior transmission in B lymphocytes
22
Q

A product in which the leukocyte is reduce in the blood to prevent alloimmunization to HLA antigens

A

Leukocyte Reduce RBC

23
Q

Volume of Leukocyte Reduce RBC

A

Similar to Original Unit

24
Q

Shelf life of Leukocyte Reduce RBC

A

Similar to Original Unit if Closed system is used

25
Q

Two RBC are divided into two seperate RBC units of equal volume

A

Two/Double Unit RBC Apheresis

26
Q

Volume of Two Unit RBC apheresis

A

320ml

27
Q

True or False . Two Unit RBC apheresis is similar to Packed RBC

A

True

28
Q

Shelf life of Two Unit RBC

A

1 yr at 1-6*C

29
Q

Use if Bleeding due to quantitative and qualitative platelet disorders

A

Random Donor Platelet Concentrate

30
Q

Volume of Random Donor Platelet concentrate

A

50-70 ml

31
Q

Random Donor Platelet concentrate is used in Prophylaxis in __________ patients . Give also the value

A

Severe Thrombocytopenic Patients ( 5000-10 000/UL)

32
Q

Shelf life of Random Donor Platelet concentrate

A

5 days with constant gentle agitation

33
Q

Shelf life of Random Donor Platelet concentrate after pooling platelets pheresis

A

4 hrs

34
Q

Volume of Single Platelet

A

200-400 ml

35
Q

In Single Platelet what is the volume of plasma to maintain pH.

A

250ml to achieve pH above 6.2

36
Q

pH of Single Platelet

A

pH of above 6.2

37
Q

True or False . In Single Platelet indication is not similar to random donor platelets

A

False

38
Q

Shelf life of Single Platetlet

A

5 days @ 20-24*C with constant gentle agitation

39
Q

It is used when additional prevention of alloimmunization to HLA antigens or reduction of CMV infection risk is desired

A

Leukocyte Reduced Platelets

40
Q

Leukocyte Reduced Platelets indications

A

Per random donor or pheresis platelets

41
Q

In Leukocyte Reduced Platelets it is done immediately before transfusion ( 3 log Filtration)

A

Bedside filtration

42
Q

Volume of Granulocyte Pheresis

A

200-300ml

43
Q

Granulocyte Pheresis shelf life

A

24 hrs @20-24*C

44
Q

An apheresis product or component with only granulocytes and other WBC

A

Granulocytes pheresis

45
Q

It is used when specific coagulation factor deficiency where coagulation factors are not available

A

FFP Fresh Frozen Plasma

46
Q

Granulocytopenia with persistent fever or infection. Give na value of Granulocytes

A
47
Q

Fresh frozen plasma contains

A

All coagulation factors , Complement other plasma proteins

48
Q

Volume of Plasma Proteins

A

200-260 ml

49
Q

Shelf life of Plasma Proteins

A

1 year @ -18*C

50
Q

It is used when there is bleeding due to multiple coagulation factor Deficiency

A

Plasma Proteins

Fundamentals in Blood Bank (17 decks)

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