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Fundamentals in Blood Bank > Blood Components and Derivatives part 2 > Flashcards

Blood Components and Derivatives part 2 Flashcards

1
Q

It is the component remaining after cryoprecipitate is prepared

A

Cryopoor plasma

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2
Q

Vol of Cryopoor plasma

A

200ml

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3
Q

Shelf Life of Cryopoor Plasma

A

same as FFP 1 year -18*C or below

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4
Q

Cryopoor Plasma has a minimal concentration of what Clotting factors

A

Fibrinogen , Factor VIII and VWF

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5
Q

Fxn/Uses of Cryopoor Plasma

A

Used in patients with hemolytic uremic syndrome , Thrombotic Thrombocytopenic Purpura

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6
Q

Volume of Cryoprecipitate

A

10-15ml

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7
Q

Shelf life of Cryoprecipitate

A

1 year @ -18*C below

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8
Q

Shelf life of Cryoprecipitate after thawing

A

6hrs

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9
Q

Cryoprecipitate used when there is congenital or acquired deficiencies of _______ and Factor ______

A

Fibrinogen and Factor XIII

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10
Q

Maybe benefecial in bleeding due to uremic platelet dysfunction not responding to desmopressin, estrogen

A

Cryoprecipitate

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11
Q

Uses of Cryoprecipitate

A

VWF , Hemophilia A when virus inactivated factor concentrates are not available
Deficiency in Factor 1 and 13

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12
Q

Volume of Factor VIII ( Lyophilized)

A

25 ml of sterile diluents for reconstitution

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13
Q

Shelf life of Factor V111 ( Lyophilized )

A

2years @ 2-8*C

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14
Q

Factor IX complex

A

Factor 2, 7, 9 and other proteins

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15
Q

Used to treat hemophilia B and patients with inhibitors to factor 8 and 9

A

Plasma derived factor 9

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16
Q

Antithrombin 3 concentrate are prepared from pooled human plasma by __________

A

Modified cold ethanol fractionation

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17
Q

In Antithrombin 3 concentrate treatment is for prophylaxis of thrombotic events in patient w/ congenital antithrombin deficiency . What are these congenital antithrombin defeciency

A

DIC , Heparin resistance , Sepsis , Deep Vein thrombosis , Pulmonary Embolism

18
Q

Antithrombin 3 concentrate volume

A

Volume per manufacturers direction

19
Q

What is the purpose of Solvent/Detergent treatment to plasma

A

To deactivate lipid enveloped viruses ( HIV , HCV)

20
Q

Vol. of S/D treated plasma

A

200 ml

21
Q

Shelf life of S/D treated plasma

A

1 year @-18 *C

22
Q

True or False . S/D treated plasma has minimal content of Low Molecular Weight VWF

A

False S/D treated plasma has minimal content of High Molecular Weight VWF

23
Q

Plasma as in FFP , stored and released for use after donor has been retested negative for viral markers after days or more , allowing for window period infections to seroconvert

A

Donor Retested Frozen Plasma

24
Q

In Donor Restested Frozen Plasma .donor has been retested negative for viral markers after_____ days or more , allowing for window period infections to seroconvert

A

112 days

25
Q

Volume of Donor Retested Frozen Plasma

A

200-260 ml

26
Q

Difference between Donor Retested Frozen Plasma and FFP

A

Donor Retested Frozen Plasma has lower risks of viral transmission than FFP

27
Q

Albumin Shelf life

A

5 years @ 2-10*C

28
Q

Volume of Albumin

A

250-500ml

29
Q

How many % of albumin and globulin are there in Plasma Protein Fraction

A

83 % Albumin , 17 % globulin

30
Q

In Plasma Protein Fraction Hypotension may occur when givent at males over __ml/min

A

10 ml/min

31
Q

Plasma Protein Fraction shelf life

A

3 years below 30*C

32
Q

Plasma Protein Fraction volume

A

250-500ml

33
Q

Albumin contraindications

A

Dehydrated Patients

34
Q

Used in Primary humoral immunodeficiency, ITP , Bone marrow transplant and pediatric HIV infection

A

Immunoglobulin Intravenous

35
Q

Immunoglobulin Intravenous volume

A

10-200ml

36
Q

Shelf life of Immunoglobulin Intravenous

A

3 years @ 2-8*C

37
Q

Immunoglobulin Intravenous gained acceptance in the treatment of ______

A

Guillain Barre’s Syndrome

38
Q

Immunoglobulin Intravenous antibodies

A

Mostly IgG , Traces of IgA and IgM

39
Q

Uses of Rh Ig

A

Prevents Rh alloimmunization of Rh neg. individual exposed to the D antigen
Used to prevent HDN

40
Q

IgG anti-Rho full dose is ___µg , minidose is ____µg

A

300µg and 50µg

41
Q

Volume of Rh Ig

A

1ml

42
Q

Shelf life of Rh Ig

A

1/2 years @ 2-8*C

Fundamentals in Blood Bank (17 decks)

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