Regulation of the Cardiovascular System 2

Question 1

Potent vasodilator

Answer 1

Nitric Oxide- Produced in vascular endothelium by nitric oxide synthase

Question 2

NO is anti-atherogenic; decreased NO associated with greatly increased risk for _____

Answer 2

atherosclerosis

Question 3

Nitric oxide synthase highly susceptible to CV disease risk factors e.g., components of____

Answer 3

cigarette smoke.

Question 4

Endothelin

Answer 4

potent vasoconstrictor, produced by vascular endothelium

Question 5

Angiotensin I cleaved by Angiotensin Converting Enzyme (ACE) to _______= vasoconstrictor.

Answer 5

Angiotensin II

Question 6

Angiotensin II is a

Answer 6

vasoconstrictor.

Question 7

ACE inhibitors & Angiotensin II receptor blockers = Therapeutics for treatment of _________

Answer 7

hypertension & heart failure

Question 8

Angiotensin I cleaved by ________ to Angiotensin II (AII) = vasoconstrictor.

Answer 8

Angiotensin Converting Enzyme (ACE)

Question 9

ALDOSTERONE

a steriod hormone that promotes Na and water resulting in ________

Answer 9

Increases blood volume and blood pressure

Question 10

ANTI-DIURETIC HORMONE (ADH, Arginine Vasopressin)

Answer 10

Increases water reabsorption in kidney
increases blood volume and pressure
Vasoconstrictor