Infectious/Inflam Myocarditis Flashcards
inflammation of heart muscle.
Myocarditis or inflammatory cardiomyopathy
______ virus is a common cause of Myocarditis or inflammatory cardiomyopathy
coxsackievirus
Typical viral causes are Coxsackievirus A or B or other enteroviruses cause:
Infection of the heart
Parasitic Myocarditis
Chagas Disease
Trichinosis
Chagas Disease
can be a common cause of heart failure (even decades later)
Tropical parasitic disease (Trypanosoma cruzi)
_____ is a common fungus to damage the heart
candida
Systemic Autoimmune disease vs heart
Lupus
RA
Scaralderma
Variable involvement of pericardium, myocardium, endocardium
Organ Autoimmunity vs herat
Goodpasture
Vasculitis leading to infarct
__________ is a toxic metabolite of the heart
Alcohol (ETOH)
Adriamycin - chemotherapeutic drug used to common cause ________ but is not used much now
cardiac problems
Toxic levels of ______ from fake joints has lead to cardiac issues
Cobalt from artificial joint prostheses
Hemochromatosis
congential
body stores too much iron
Hemochromatosis will have too much ___ staining
Blue
Iron Stain: Excess pigment is iron.
Amyloidosis is a
Protein deposition as “beta-pleated sheets”
Special Stain Characterization of Deposits Amyloidosis
Congo Red Stain
Non-Polarized
- Deposits: “Salmon Orange” color
Congo Red Stain Polarized
- Deposits: “Granny apple green”
Birefringence
body absorbs too much iron. The excess iron is stored in liver, heart and pancreas.
The excess iron can poison these organs, leading to life-threatening conditions such as cancer, heart arrhythmias and cirrhosis.
Hemochromatosis
“beta-pleated sheets” protein build up is common in
Amyloidosis- Not specific for identity of protein
affects . Heart/Kidneys–> morbidity
Amyloids impair in the heart
conduction
contractility
“Granny apple green” stain means
Amyloids
