regulation of stroke volume and heart rate Flashcards
What sets the heart rate
The pacemaker cells of the sinoatrial node which cause the atria to contract and then the ventricles after the delay from the atrioventricular node
Describe the sympathetic innervation of the heart
- Symopathetic nerves release noradrenaline
- circulating adrenaline from the adrenal medulla
- Both act on B1 receptors on the sinoatrial heart and increase the heart rate
Describe the parasympathetic innervation of the heart
- Vagus nerves release acetylcholine
- Acts on muscarinic receptors of the SA node
- Hyperpolarises cell and causes decreased heart rates
What is the stroke volume
Volume of blood pumped from the left ventricle per heart beat - the difference between end diastolic and systolic volume
What is after load
The load against which the heart muscles try to contract against
What is the result of the TPR - total peripheral resistance increasing
The aortic pressure will increase - the ventricle will have to work harder to push open the aortic valve and there will be less energy to eject the blood - the stroke volume will decrease
What is the preload
How full the ventricle is before it begins to contract
What is the cardiac output
Heart rate x stroke volume - stroke volume affects the cardiac output more