clinical pharmacology of stable coronary disease

Question 1

What is is the presentation of stable angina

Answer 1

• predictable ischaemic chest pain (heavy tight band like) precipitated by exercise or emotional stress which increases the myocardial oxygen demand
• Good response to GTN spray

Question 2

What is used to treat the symptoms of stable angina

Answer 2

• Beta blockers
• Calcium channel blockers (myocardium specific - verapamil)
• Calcium channel blockers (vasodilator - amlodepine)
• GTN (Nitratea)

Question 3

What is given for disease modification of stable angina

Answer 3

Antiplatelets:
1. aspirin
2. clopidogrel
3. ticagrelor

Statins