Regulation of Reproduction - Neuroendocrinology Flashcards

1
Q

Pathways for simple neural reflex

A
Stimulus
Sensory neurons
Transmission (internuerons)
Efferent nurons
Neurotransmitter
Target tissue
Response by target tissue
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2
Q

Pathway for neuroendocrine reflex

A
Stimulus
Sensory neurons
transmission
Efferent neurons
Hypothalamus
Neurohormone
blood
target tissue
response by target tissue
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3
Q

Oxytocin produced where

A

Hypothalamus

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4
Q

LH, FSH, ACTH, PRL, GH, TSH

A

Anterior pituitary

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5
Q

Hormone definition

A

Substance produced by special cells thats carried in the blood stream and affects activity of body function

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6
Q

Endocrine gland

A

Gland that produces hormones

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7
Q

Reproductive hormone traits

A
Small quantities
Influence each other
Provide feedback 
Short half lives
Bind to specific receptors
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8
Q

Top 6 Repro Hormones

A
Driver - GnRH
Stimulator - FSH
Ovulator 0 LH
Receptor - E2
Regulator - Progesterone P4
Terminator -Prostaglandin PGF2a
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9
Q

Classification of hormones

A
Neurpeptides
Proteins
Glycoproteins
Prostaglandins
Steriods
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10
Q

How are hormones classified

A

Based on source/origin

Hypothalomic
pituritay
gonodal
uterine
placental
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11
Q

Hypothalamus

A

Released GnRH
Tonic center and surge center
Acts on anterior pituitary

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12
Q

Surge Center

A

Sensitive to positive feedback

Secretes high amplitude and high frequency GnRH

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13
Q

Tonic Center

A

Small secretion of GnRH

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14
Q

Anterior Pituitary

A

has Portal system

LH, FSH, Prolactin

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15
Q

Posterior Pituitary

A

No Portal system

Oxytocin and vasopression

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16
Q

Neurohormones

17
Q

Releasing hormone

18
Q

Gonadotrphin hormones

19
Q

Pregnancy maintenance hormones

A

Progesterone

P4

20
Q

Luteolytic hormones

21
Q

Hormones stimulating maternal ovaries

22
Q

Oestrogen action

A

Female receptivity, secondary sex characters, female sexual behavior

23
Q

Progesterone action

A

Sexual behavior, pregnancy maintenance

24
Q

Testosterone action

A

Sexual behaviour, spematogenesis

25
Prostaglandin
CL regression, uterine contractions
26
Inhibin action
Inhibits FSH release
27
Strength of hormone action depends on
Half life Duration on secretion Receptor-hormone affinity Receptor density
28
Pheromones
Volatile substances excreted to outside atmosphere Affect repro performance Enhance puberty
29
Female Feedback
CL releases P4 negative to hypothalamus | Follicle releases E2 (positive feedback)
30
Negative feed back
CL releases P4 | Supression of GnRH neurons
31
Positive feedback
Stimulaiton of GnRH neurons
32
High negative feedback(P4) release from CL causes:
Inhibits GnRH neurons = on secrete basal level on GnRH = no FSH and Low LH = little follicular development (pregnant or midcycle)
33
hIGH POSITIVE FEEDBACK (E2) from follicle =
Enhances GnRH = LH and FSH secretion causing ovulation