Regulation of Feeding Flashcards
1
Q
hypothalamic feeding center
A
- lateral nuclei
2
Q
stimulation of lateral nuclei
A
- hyperphagia
3
Q
destruction of lateral nuclei
A
- inanition
4
Q
hypothalamic satiety center
A
- ventral nuclei
5
Q
stimulation of ventral nuclei
A
- refusal to eat
6
Q
destruction of ventral nuclei
A
- overeating
7
Q
lesion to paraventricular nucleus
A
- increases eating
8
Q
lesion to dorsal medial nucleus
A
- decreases eating
9
Q
orexigenic substances
A
- stimulate feeding
10
Q
anorexigenic substances
A
- inhibit feeding
11
Q
activation of AGRP/NYP neurons
A
- increase feeding
- low energy stores: NPY released, reduce POMC firing leading to appetite stimulation
12
Q
activation of POMC/CART neurons
A
- decrease feeding while increasing energy expenditure
13
Q
mutations in MCR receptors
A
- leads to hyperphagia
14
Q
C peptide
A
- secreted with insulin
- longer half life
- used as measure of insulin secretion
15
Q
somatostatin
A
- inhibits both insulin and glucagon
- secreted from delta cells
16
Q
IDDM (type 1)
A
- lack of insulin secretion - destruction of beta cells
- onset at puberty
- increased blood glucose
- treat with insulin replacement
17
Q
NIDDM (type 2)
A
- decreased sensitivity of target tissue to insulin
- adult onset
- increased plasma insulin (initially) and glucose
- treat by altering diet, then drugs
