Regulation Of Animal Cell Shape (L6) Flashcards
What is the cytoskeleton?
- helps maintain cell shape + position of organelles within cell
- provides stability to the cell while still being dynamic
- allows rapid changes in cell shape
What are the 3 main components of the cytoskeleton?
Microtubules/microfilament/intermediate filaments
What are the main functions of the microtubule?
- maintain cell shape (by resisting compression
- provide cell motility
- involved in organelle motility (via ATP) (allows vesicles to transport proteins across the cell)
This resists tension and forms a cortical network under the plasma membrane which makes it less fluid and maintains cell shape in doing so.
Microfilalments
These are made of various proteins. Usually supercoiled into cables which form relatively permanent cellular structures.
Intermediate filaments
What are the 3 major types of cell junctions?
Tight junctions, gap junctions, desmosomes
What is the difference between tight junction/gap junction/desmosome?
Tight junctions - cells are tightly pressed together; prevents movement of fluid across cell layers
Desmosomes - anchoring junctions; provides attachments between sheets of cells; connected into the cell via intermediate filaments
Gap junctions - a point of contact between two cells where ions and small molecules can be passed; allows rapid cell to cell communication
Where do cells lie?
extracellular matrix
What is the most abundant glycoprotein in the ECM?
collagen
These are proteins with carbohydrates
Glycoproteins
What are collagen fibres embedded on? What are their functions?
Proteoglycan complex matrix (like a branched matrix). They trap water in the ECM, which resists compression and helps retain tissue shape.
A form of glycoprotein (kinda like a dinosaur which attaches cells to the ECM
Fibroconectins
These connect ECM to cytoskeleton
Integrin/membrane proteins
What are non-animal functions of microfilaments?
Amoeboid movement and cytoplasmic streaming in plants
An ________ is less dynamic than microtubules or microfilaments.
Intermediate filament
T/F: Intermediate filaments may remain after the cell that made them has died.
True
Microfilaments resist ______
Tension
What are the 3 types of cell junctions?
Gap junction, desmosome, tight junctions
Desmosomes are connected into the cell through?
a) microfilaments
b) intermediate filaments
c) gap junctions
Intermediate filaments
This is a point of cytoplasmic contact between two cells and allows rapid cell to cell communication.
Gap junctions
The extracellular matrix composition varies between tissues. T/F:
True
These are proteins with extensive sugar additions, they trap water in the ECM. This is what the collagen in the ECM is embedded on.
Proteoglycan
_______ resists compression and thus helps retain cell shape. ________ resists tension
Water; collagen