Mitosis (L13) Flashcards
How does acellular RNA store their genetic information?
double/single stranded DNA/RNA
How do prokaryotes store genetic information?
Circular, single copy double stranded DNA.
- bacteria is usually just splotchy DNA
How do eukaryotes store genetic information?
Linear, single copy, histone-bound DNA (double strands)
How are genes packaged?
Genes are supercoiled and packaged in chromosomes.
Remember: genes are carriers of genetic inheritance.
An ordered visual representation of chromosomes in a cell
Karyotype
- some applications of karyotypes include: taking blood sample/treating cells with mitogen and colchicine (mitogen is an agent that drives mitosis.)
Location of the gene in chromosome
Locus/loci
Carries the genetic information
Gene
This is the different variations of a gene
Allele
This describes 2 identical alleles in a locus
Homozygous (homo = means the same)
This describes 2 different alleles in a locus
Heterozygous (hetero = different)
How many chromatids are there in a pair of homologous chromosomes?
Chromosomes = two sister chromatids held by the centromere
Homologous = similar chromosome
There are four chromatids in a homologous pair
What are the sex chromosomes?
X & Y
How many chromosomes are there in a human cell?
23 pairs. So 46 chromatids
What are the two main functions of cell division for multicellular organisms?
Growth and development
Tissue renewal
What is the cell cycle?
An overview of how cells divide. Composed of:
G1 Phase — S Phase — G2 Phase — Mitotic Phase
What happens at each phase of the cell cycle?
Interphase = longest phase of cell cycle; most of the time a cell is in interphase: comprised of 3 phases
- G1 Phase = the cell grows
- S Phase = DNA replicates, chromosomes duplicate, the organelles duplicate
- G2 Phase = enzymes get ready for mitosis
Mitotic Phase = mitosis and cytokinesis
- Mitosis has 5 phases (Prophase, Prometaphase Metaphase, Anaphase, Telophase)
- Cytokinesis = where the cytoplasm breaks apart
At what phase does the cell replicate all its contents? (Including DNA and organelles)
S Phase of Interphase
At what phase does the cell divide and form its own nuclear envelope/cytoplasm?
Mitotic Phase = mitosis + cytokinesis
What happens at G2 of Interphase?
Chromosomes are duplicated but uncondensed from the chromatin fibres.
This is the phase of mitosis where the Mitotic spindle forms and two chromosomes are condensed in the chromatin fibre
Prophase
Phase of mitosis where kinetichore microtubules connects to the centromere to hold sister chromatids and pull them to opposite sides of the cell.
The non-kinetochore microtubules shorten when the kinetochore microtubules lengthen. And likewise.
Prometaphase
This phase of mitosis is when the sister chromatids line up at the metaphase/equatorial plate.
Metaphase
This phase is when the kinetochore microtubules break the sister chromatids apart. Each pole will get one copy of DNA
Anaphase
This phase is when the cell divides. A cleavage furrow forms along with a nucleolus and nuclear envelope.
Telophase