Red Ulcerated Lesions Flashcards
What is epidermolysis bullosa? Characteristics?
Congenital defect in the attachement of the epithelial cells.
- Vesicles and bullae due to minor trauma.
- There is a spectrum of this disease.
What are the characteristics of viral diseases?
- Acute onset
- Lymphadenopathy
- Multiple ulcers
- All have vesicle stage
What is the steps of herpes simplex?
- Primary infeciton
- Latency: Virus takes up by nerves.
- Recurrent: Effects epi supplied by sensory ganglion.
What are the characteristics of primary herpetic gingivostomatitis?
- Lymphadenopathy present
- Numerous pihead vesicles and ulcers in oral cavity on keratinized AND non-keratinized (BOTH).
What are the characteristics of recurrent herpes simplex?
- Prodrome: tingling or burning sensation.
- Vesicles and ulcers in small clusters ONLY on Keratinized tissue.
- Recur in same location each time
- Lymphadenopathy not present.
What is herpetic whitlow, Herpes gladatorium, Herpes babrae,
W:Herpes simplex on the finger.
G: Herpes common in wrestlers or rugby players.
B: herpes in the beard area due to razor cuts.
What is Varicella (chickenpox) and what causes it?
Successive crops of puritic papules, vesicles, ulcers on the skin.
-Caused by Varicella-Zoster HHV-3.
What is herpes zoster (Shingles)? What kind of distribution? What can occur as a lingering effect?
Recurrence of HHV-3
- Unilateral Distribution.
- Post-herpetic neuralgia: Chronic severe nerve pain.
What is infectious mononucleosis? Caused by? Associated with? Oral mucosa findings?
- Epstein-barr virus by HHV-4.
- Associated with: Burkitt’s lymphoma, Nasopharyngeal carcinoma, Hairy leukoplakia.
- Erythematous, petichiae, ulcers without vesicles.
- Cervical lymphadenopathy
What is hand, foot, and mouth disease? Caused by? Characteristic lesions?
- Coxsackievirus, group A
- Vesicles and lesions in oral cavity, with macules and vesicles on hands and feet.
- Flu like symptoms
What is Herpangina? Caused by? Locations in mouth?
- Similar to HFM but confined to posterior oral cavity.
- Caused by coxsackievirus group A.
- Soft palate, uvula, tonsillar pillar. ONLY NON-KERATINIZED
What is Measels (Rubeola) caused by? Characteristics?
viral infection caused by Paramyxovirus.
- Koplik’s spots
- Mycosal erythema
- small blue-white macules that look like grains of salt.
What are the characteristics of autoimmune diseases?
- Gradual onset
- Progressive
- Controlled with corticosteroids.
What is the cause of erosive lichen planus? Oral lesion characteristics?
- Immune abnormality involving T lymphocytes.
- White striae along periphery
- Vesicles are rare
- Bilateral
What is pemphigus vulgaris? Characteristics? Present under microscope? Treatment?
Autoantibodies attack desmosomes.
- Blisters rupture easily
- Multifocal
- Nikolsky sign sometimes present.
- Tzanck cells present.
Treat with corticosteroids.
What is mucous membrane pemphigoid? Characteristics?
Antibodies against basal lamina hemidesmosomes.
- Can cause eye lesions.
- Generalized vesicles and painful ulcers.
What is bullous pemphgioid? Characteristics?
same as MMP, but more limited and no scaring.
-Most common auto-immune blistering condition.
What is systemic lupus erythematosus?
-Multisystem autoimmune disease with increased B lymphocyte activity and abnormal T cell function.
What is chronic cutaneous lupus erythematosus? can cause?
Autoimmune disease, limited to skin and mucosal surfaces.
-Can cause scarring and pigmentation
What are some additional characteristics of lupus?
- Kidney failure
- Butterfly rash
- Cardiac involvement
- Gingival lesions.
What is riga-fede disease?
-dramatic ulcer on infants with neonatal teeth.
What is chronic erythematous candidosis?
-Chronic candida due to denture wearing.
What is angular cheilitis?
Saliva pools at corner of the mouth and fungus and bacteria cause infection there.
What is candida median rhomboid glossitis?
a posterior lesion on the tongue caused by candida.
