Red Cell Disorders 2 Flashcards
How can the hemoglobin be classified?
What is sickle cell disease ?
What are the types of sickle cell?
Discuss the pathogenesis of sickle cell disease
Discuss the peripheral blood smear for sickle cell disease
What factors affect sickling in sickle cell disease?
What are the clinical features of sickle cell disease ?
What are the symptoms of sickle cell trait?
What symptoms are associated with sickle cell disease?
What usually precipitates Sickle cell crises?
What’s the vaso-occlusive/painful crises?
What’s a sequestration crises in a sickle cell disorder?
What is aplastic crises for sickle cell crises?
What’s hemolytic crises of sickle cell disease?
What is a sickle cell disease diagnose based on?
What are the diagnosis of sickle cell disease?
How do we treat sickle cell disease?
What’s the clinical outcome of homozygous sickle cell disease?
What are thalassemia syndromes?
What is B-thalassemia?
What are the clinical syndromes of B-thalassemia?
What is B-thalassemia major?
What is the pathogenesis of B-thalassemia?
What are the clinicopathogenesis of B-thalassemia major?
What’s the diagnosis of B-thalassemia based on?
What’s the lab findings of Hb electrophoresis of B-thalassemia major?
What is B-thalassemia minor?
Describe B-thalassemia clinical course & treatment
What is alpha-thalassemia?
What is a-thalassemia minima?
What is a-thalassemia minor?
Contrast hemoglobin H and hemoglobin Barts
What are the clinical features of a-thalassemia minima?
What are the clinical features of a-thalassemia minor?
What are the clinical features of Hemoglobin H ?
What are the clinical features of hemoglobin Barts?
What is Paroxysmal Nocturnal Heamoglobinuria?
Describe the pathogenesis of Paroxysmal Nocturnal Hemoglobinuria
What are the clinical features of Paroxysmal Nocturnal Hemoglobinuria ?
How can we diagnose paroxysmal nocturnal Hemoglobinuria?
What are the associated conditions of paroxysmal nocturnal Hemoglobinuria?
Is thalassemia intra or extravascular?
Extravascular