Red Cell Disorders 2

Question 1

How can the hemoglobin be classified?

Answer 1

Question 2

What is sickle cell disease ?

Answer 2

Question 3

What are the types of sickle cell?

Answer 3

Question 4

Discuss the pathogenesis of sickle cell disease

Answer 4

Question 5

Discuss the peripheral blood smear for sickle cell disease

Answer 5

Question 6

What factors affect sickling in sickle cell disease?

Answer 6

Question 7

What are the clinical features of sickle cell disease ?

Answer 7

Question 8

What are the symptoms of sickle cell trait?

Answer 8

Question 9

What symptoms are associated with sickle cell disease?

Answer 9

Question 10

What usually precipitates Sickle cell crises?

Answer 10

Question 11

What’s the vaso-occlusive/painful crises?

Answer 11

Question 12

What’s a sequestration crises in a sickle cell disorder?

Answer 12

Question 13

What is aplastic crises for sickle cell crises?

Answer 13

Question 14

What’s hemolytic crises of sickle cell disease?

Answer 14

Question 15

What is a sickle cell disease diagnose based on?

Answer 15

Question 16

What are the diagnosis of sickle cell disease?

Answer 16

Question 17

How do we treat sickle cell disease?

Answer 17

Question 18

What’s the clinical outcome of homozygous sickle cell disease?

Answer 18

Question 19

What are thalassemia syndromes?

Answer 19

Question 20

What is B-thalassemia?

Answer 20

Question 21

What are the clinical syndromes of B-thalassemia?

Answer 21

Question 22

What is B-thalassemia major?

Answer 22

Question 23

What is the pathogenesis of B-thalassemia?

Answer 23

Question 24

What are the clinicopathogenesis of B-thalassemia major?

Answer 24

Question 25

What’s the diagnosis of B-thalassemia based on?

Answer 25

Question 26

What’s the lab findings of Hb electrophoresis of B-thalassemia major?

Answer 26

Question 27

What is B-thalassemia minor?

Answer 27

Question 28

Describe B-thalassemia clinical course & treatment

Answer 28

Question 29

What is alpha-thalassemia?

Answer 29

Question 30

What is a-thalassemia minima?

Answer 30

Question 31

What is a-thalassemia minor?

Answer 31

Question 32

Contrast hemoglobin H and hemoglobin Barts

Answer 32

Question 33

What are the clinical features of a-thalassemia minima?

Answer 33

Question 34

What are the clinical features of a-thalassemia minor?

Answer 34

Question 35

What are the clinical features of Hemoglobin H ?

Answer 35

Question 36

What are the clinical features of hemoglobin Barts?

Answer 36

Question 37

What is Paroxysmal Nocturnal Heamoglobinuria?

Answer 37

Question 38

Describe the pathogenesis of Paroxysmal Nocturnal Hemoglobinuria

Answer 38

Question 39

What are the clinical features of Paroxysmal Nocturnal Hemoglobinuria ?

Answer 39

Question 40

How can we diagnose paroxysmal nocturnal Hemoglobinuria?

Answer 40

Question 41

What are the associated conditions of paroxysmal nocturnal Hemoglobinuria?

Answer 41

Question 42

Is thalassemia intra or extravascular?

Answer 42

Extravascular