Chemotherapy If Neoplastic Diseases 3 Flashcards

1
Q

What’s the role of microtubules in mitosis?

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2
Q

What are microtubule inhibitors?

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3
Q

What are the vinca alkaloids?

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4
Q

What’s the MOA on vinca alkaloids?

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5
Q

What are the adverse effects of vincristine?

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6
Q

What are the AE of vinblastine?

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7
Q

What are taxanes?

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8
Q

What are the MOA of taxanes?

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9
Q

What are the adverse effects of taxanes?

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10
Q

What are the anti cancer drugs ?

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11
Q

What are epipodophyllotoxins?

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12
Q

What are the AE epipodophyllotoxins?

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13
Q

What are camptothecins?

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14
Q

What are the categories of hormonal. Agents?

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15
Q

What glucocorticoids are to be used in chemotherapy?

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16
Q

What are the estrogen inhibitors?

17
Q

What are the SERMs?

18
Q

What are Tamoxifen?

19
Q

What are the AE of SERMs?

20
Q

What are the strong inhibitors of CYP2D6?

21
Q

What are the uses of Raloxifene?

22
Q

What are the AE of Raloxifene?

23
Q

What is fulvestrant?

24
Q

What’s the use of Aromatase inhibitors?

25
Q

What are the examples of Aromatase inhibitors?

26
Q

What are the categories of androgen inhibitors?

27
Q

What are the gonadotropin-releasing hormone agonists?

28
Q

How can the flare phenomenon be counteracted in gonadotropin-releasing hormone agonists?

29
Q

What are the uses of gonadotropin-releasing hormone agonists?

30
Q

What is glutamine in androgen receptor blockers?

31
Q

What are receptor tyrosine kinases?

32
Q

What are the tyrosine kinase inhibitors & monoclonal antibodies?

33
Q

What are the inhibitors of receptor tyrosine kinases?

34
Q

What is asparaginase?

35
Q

What are the adverse effects of asparaginase?

36
Q

What is hydroxyurea?

37
Q

What are the uses of interferons?

38
Q

What are the key drugs of choice for cancer?