RBC disprders 1 Flashcards

1
Q

What is anemia?

A
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2
Q

What are the clinical features of anemia ?

A
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3
Q

What are the signs of anemia?

A
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4
Q

What are the useful RBC parameters?

A

MCV, MCH, MCHC, RDW

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5
Q

What is MCV?

A
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6
Q

What is MCH?

A
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7
Q

What is MCHC?

A
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8
Q

What is RDW?

A
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9
Q

What can anemia be classified based on?

A
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10
Q

What is the morphological classification of anemia?

A
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11
Q

What are the morphological classifications of anemia?

A
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12
Q

What see the causes microcytic hypochromic anemia?

A
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13
Q

What’s the causes of normocytic normocyromic anemia ?

A
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14
Q

What’s the cause of normochromic macro cystic anemia?

A
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15
Q

How can anemia be classified by the underlying mechanism?

A
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16
Q

What are the ways can anemia be due to blood loss?

17
Q

What are the common features of hemolytic anemia?

18
Q

Contrast intravascular & extravascular hemolysis

19
Q

What is the laboratory evidence of hemolytic anemia?

20
Q

How are intravascular & extravascular hemolysis different in laboratory readings?

21
Q

Contrast intrins8c & extrins8c defeceits in RBC defects

22
Q

What is hereditary Spherocytosis?

23
Q

Describe the pathogenesis of hereditary spherocytosis

24
Q

What are the c,II cal features of hereditary spherocytosis?

25
Discuss diagnosis and lab findings of hereditary spherocytosis
26
How can Osmotic fragility test be used to diagnose hereditary spherocytosis?
27
How can Coombs test be used to be used to diagnose hereditary spherocytosis?
28
What is Glucose-6-phosphate dehydrogenase deficiency?
29
How does G6PD deficiency affect RBCs?
30
Discuss the pathophysiology of G6PD deficiency
31
Discuss the clinical presentation of G6PD
32
Discuss diagnosis & lab findings of G6PD deficiency