Recreational Drugs

Question 1

What are the classes of drugs and their examples?

Answer 1

•Stimulants
-Cocaine, ecstasy, nicotine, caffeine, khat.
•Depressants
-Barbiturates, ethanol
•Inhalants
-Glue, thinners, petrol
•Opiates
-Heroine
•Cannabinols
-Marijuana, hashish
•Hallucinogens
-LSD, psilocybin, mescaline
•Dissociative
-PCP, dextramethorphan, ketamine
•Other: Whoonga, nyaope

Question 2

What was the main ingredient of the original coca-cola?

Answer 2

Cocaine

Question 3

Clinical use of cocaine?

Answer 3

Used as a local anaesthetic in eye surgery, causes vasoconstriction.

Question 4

Name the three metabolites of cocaine as well as how they are formed.

Answer 4

•Benzoylecgonine which is formed from spontaneous hydrolysis.
•Ecgonine methyl ester which is formed from metabolism by pseudocholinesterase.
•Norcocaine which is formed from metabolism by the p450 system.

Question 5

Effects of cocaine (4)

Answer 5

Vasoconstrictive, neurotoxic, cardiotoxic and dsyrhythmogenic

Question 6

Three mechanisms in which cocaine’s effects occur

Answer 6

Blockage of reuptake of biogenic amines.
Blockage of sodium channel.
Excitatory amino acid stimulation.

Question 7

What are some of the effects of marijuana? (5)

Answer 7

-Ataxia
-Dry mouth
-Increased appetite
-Conjunctival injection (red eyes)
-Slurred speach

Question 8

What are some of the effects of heroine? (4)

Answer 8

-Slurred speech
-Sedative (“nodding)
-Pinpoint pupils
-Euphoria