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0. Step Ib > Receptors & signaling molecules > Flashcards

Receptors & signaling molecules Flashcards

1
Q

Signaling pathway of: PTH

A

cAMP

“FLAT ChAMP” likes to cAMP

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1
Q

Signaling pathway of: glucagon

A

cAMP

“FLAT ChAMP” likes to cAMP

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1
Q

Signaling pathway of: Estrogen

A

steroid (intracellular) receptor

“VETTT CAP”

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1
Q

Signaling pathway of: Progesterone

A

steroid (intracellular) receptor

“VETTT CAP”

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1
Q

Signaling pathway of: FGF

A

Intrinsic tyrosine kinase (TK), MAP kinase pathways

“growth factors” - in order to grow, you need insulin, growth factors, and a good MAP

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1
Q

what receptors activate Adenylyl cyclase? inhibits?

A

activate: Receptor Gs (β1, β2, D1, H2, V2)
inhibit: Gi (M2, α2, D2)

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3
Q

Signaling pathway of: Histamine

A

IP3

“A TOGA is HH-IP3 (hippy)”

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4
Q

H1

A

G protein class: q

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5
Q

D2

A

G protein class: i

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6
Q

Signaling pathway of: CRH

A

cAMP

“FLAT ChAMP” likes to cAMP

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6
Q

Signaling pathway of: ADH (V1)

A

IP3

“A TOGA is HH-IP3 (hippy)”

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6
Q

Signaling pathway of: IL-6

A

Receptor-ASSOCIATED tyrosine kinase pathways (ie JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
know that PIG signals thorugh a separate pathway than FLAT

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7
Q

Signaling pathway of: epinephrine

A

cAMP

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7
Q

Signaling pathway of: ANP

A

cGMP

“vasodilators”

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7
Q

Signaling pathway of: IL-2

A

Receptor-ASSOCIATED tyrosine kinase pathways (JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
<span>know that PIG signals thorugh a separate pathway than FLAT</span>

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7
Q

Signaling pathway of: GH

A

Receptor-ASSOCIATED tyrosine kinase pathways (JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
know that PIG signals thorugh a separate pathway than FLAT

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8
Q

Signaling pathway of: IL-8

A

Receptor-ASSOCIATED tyrosine kinase pathways (JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
know that PIG signals thorugh a separate pathway than FLAT

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9
Q

Signaling pathway of: Angiotensin II

A

IP3

“A TOGA is HH-IP3 (hippy)”

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10
Q

Signaling pathway of: GHRH

A

cAMP

“FLAT ChAMP” likes to cAMP

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12
Q

Signaling pathway of: Cortisol

A

steroid (intracellular) receptor

“VETTT CAP”

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13
Q

Signaling pathway of: Testosterone

A

steroid (intracellular) receptor

“VETTT CAP”

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14
Q

β1

A

G protein class: s

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15
Q

Signaling pathway of: ACTH

A

cAMP

“FLAT ChAMP”

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17
Q

Receptors that signal through Gi?

A

Gi (M2, α2, D2) - decrease cAMP

17
Q

Signaling pathway of: TSH

A

cAMP

“FLAT ChAMP” likes to cAMP

19
Q

α2

A

G protein class: i

20
Q

D1

A

G protein class: s

21
Q

V2

A

G protein class: s

21
Q

Signaling pathway of: NO (EDRF)

A

cGMP

“vasodilators”

22
Q

Signaling pathway of: T3/T4

A

steroid (intracellular) receptor

“VETTT CAP”

23
Q

M3

A

G protein class: q

25
Q

V1

A

G protein class: q

26
Q

Signaling pathway of: Gastrin

A

IP3

“A TOGA is HH-IP3 (hippy)”

27
Q

Signaling pathway of: Vitamin D

A

steroid (intracellular) receptor

“VETTT CAP”

28
Q

Signaling pathway of: PDGF

A

Intrinsic tyrosine kinase (TK), MAP kinase pathways

“growth factors” - in order to grow, you need insulin, growth factors, and a good MAP

30
Q

Signaling pathway of: LH

A

cAMP

“FLAT ChAMP” likes to cAMP

31
Q

Signaling pathway of: hCG

A

cAMP

“FLAT ChAMP” likes to cAMP

32
Q

Signaling pathway of: IGF-1

A

Intrinsic tyrosine kinase (TK), MAP kinase pathways

“growth factors” - in order to grow, you need insulin, growth factors, and a good MAP

34
Q

Signaling pathway of: Aldosterone

A

steroid (intracellular) receptor

“VETTT CAP”

35
Q

Receptors that signal through Gq?

A

Gq = H1, a1, V1, M1, M3 -> DAG/IP3

“HAVe 1 M&M”

36
Q

Signaling pathway of: FSH

A

cAMP

“FLAT ChAMP” likes to cAMP

37
Q

Signaling pathway of: EGF

A

Intrinsic tyrosine kinase (TK), MAP kinase pathways

“growth factors” - in order to grow, you need insulin, growth factors, and a good MAP

38
Q

Signaling pathway of: ADH (V2)

A

cAMP

“FLAT ChAMP”

40
Q

what receptors activates the IP3 pathway?

A

Gq = H1, a1, V1, M1, M3

“HAVe 1 M&M”

42
Q

β2

A

G protein class: s

44
Q

Signaling pathway of: MSH

A

cAMP

“FLAT ChAMP” likes to cAMP

45
Q

M1

A

G protein class: q

47
Q

H2

A

G protein class: s

49
Q

Signaling pathway of: oxytocin

A

IP3

“A TOGA is HH-IP3 (hippy)”

50
Q

Receptors that signal through Gs?

A

Receptor Gs (β1, β2, D1, H2, V2) -> cAMP

51
Q

Signaling pathway of: calcitonin

A

cAMP

“FLAT ChAMP” likes to cAMP

52
Q

Signaling pathway of: Prolactin

A

Receptor-ASSOCIATED tyrosine kinase pathways (ie JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
know that PIG signals thorugh a separate pathway than FLAT

53
Q

α1

A

G protein class: q

54
Q

Signaling pathway of: GnRH

A

IP3

“A TOGA is HH-IP3 (hippy)”

55
Q

Signaling pathway of: TRH

A

IP3

“A TOGA is HH-IP3 (hippy)”

56
Q

M2

A

G protein class: i

57
Q

Signaling pathway of: IFN

A

Receptor-ASSOCIATED tyrosine kinase pathways (ie JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
know that PIG signals thorugh a separate pathway than FLAT

58
Q

ANP, NO (EDRF) have this signaling molecule in common:

A

cGMP

59
Q

Signaling pathway of: Insulin

A

Intrinsic tyrosine kinase (TK), MAP kinase pathways

“growth factors” - in order to grow, you need insulin, growth factors, and a good MAP

0. Step Ib (19 decks)

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