autonomic receptors Flashcards
α1
VSM - vasoconstriction
GI/GU - constriction
Eye - mydriasis, aka dilation (constriction of pupillary dilator muscle!)
[theme = constriction]
α2
nerve terminals -> decr. NT release
platelets - increase aggregation
ß1
heart - increase HR, contractility
kidneys - increase renin release
[ß1: ONE heart ONE love to get your HR up]
ß2
lungs - bronchodilation [ß2: TWO lungs]
VSM - vasodilation
Uterus - relaxation (tocolysis)
[ex: Terbutaline: ß2 agonist relaxes uterine contractions -> stops premature labor]
D1
renal, splanchnic, and mesenteric BV smooth muscles -> vasodilation (increases renal + splanchnic blood flow)
[Incr RBF]
D for dilation
D2
nerve terminals & nT release in CNS
V1
VSM = increase contraction
ex: vasopressin
V2
renal CD - increase H2O uptake
[V2: 2 kidneys]
M1
CNS
enteric NS
M2
heart - decrease HR/contractility
[opposes ß1 effects]
M3
GI - increase peristalsis
GU - increase bladder contraction
lungs - bronchoconstriction
eyes - pupil sphincter
[M3 -> messy: tears, urine, sputum. H1 makes more mucous though]
H1
increase mucous production in nose, bronchus
increase vascular permeability
increase contraction of bronchioles
pain
[H1 blocker = antihistamines like diphenhydramine/Benadryl or Loratidine]
H2
increase gastric acid production
[H2 blocker: symetidine]
pupils - constrict
M3 (or α1 blockade)
pupils - dilate (mydriasis)
α1 (or M3 blockade)