Hypersensitivity Reactions Flashcards
bee sting
Type I
rhinitis
Type I
asthma
Type I
Erythroblastosis fetalis
Type II
Serum sickness
Type III
Bullous pemphigoid
Type II
SLE
Type III
nickel allergy
Type IV
Acute hemolytic transfusion reactions
Type II - due to 1) ABO incompatibility or 2) extravascular hemolysis - host antibody reaction against foreign antigen on donor RBC
sx: fever, hypotension, tachypnea, tachycardia, flank pain, hemoglobinemia (intravascular hemolysis), jaundice (extravascular hemolysis)
Multiple sclerosis
Type IV
Graft-versus-host disease
Type IV
Poststreptococcal glomerulonephritis
Type III
eczema
Type I
Allergies
Type I
Anaphylaxis
Type I
hives
Type I
Contact dermatitis (e.g., poison ivy, nickel allergy)
Type IV
Pemphigus vulgaris
Type II
Idiopathic thrombocytopenic purpura
Type II
PPD test
Type IV
food/drug allergies
Type I
Arthus reaction (e.g., swelling and inflammation following tetanus vaccine)
Type III
Autoimmune hemolytic anemia
Type II
Polyarteritis nodosa
Type III
Guillain-Barré syndrome
Type IV
poison ivy
Type IV
atopic disorders (e.g., rhinitis, hay fever, eczema, hives, asthma)
Type I
hay fever
Type I
Goodpasture syndrome
Type II
Pernicious anemia
Type II
Rheumatic fever
Type II
febrile non-hemolytic transfusion reaction
Type II - host antibodies against donor HLA antigens/leukocytes
results in fever, HA, chills, flushing
