Readings Week 1

Question 1

What affects whether an individual will deal with PTSD forever?

Answer 1

The severity of trauma, population demographics and social constraints…

Question 2

What did Cannon find?

Answer 2

Adrenal secretions act as mediators of stress.

Question 3

What is the FIT Principle?

Answer 3

Exercise of a sufficient frequency, intensity and time will induce a phenotypic adaptation in muscle.

Question 4

What is metabolic stress? What effects this?

Answer 4

The metabolic cost of exercise and substrate availability. Depends on intensity and type of exercise.

Question 5

What happens when there are higher levels of calcium in working muscle for a longer period of time?

Answer 5

Due to the all or none principle, this means the more force that can be produced and the signalling pathways.

Question 6

When is metabolic stress high and calcium flux is in repeated bursts for a short period of time?

Answer 6

Endurance training

Question 7

Why does an increase in load cause muscular hypertrophy?

Answer 7

There is more protein synthesis controlled by phosphorylation events and mTORC1.

Question 8

What are the 2 main pathways that alter calcium flux by increasing transcriptional activity?

Answer 8

Calcineurin and CAMKs