RBCs Flashcards
1
Q
FEP (protoporphyrin) is ___ in Fe deficient anemia
A
increased
2
Q
____ converts succinyl CoA to ALA
A
ALAS
3
Q
sideroblastic anemia is due to defective ___ synthesis
A
protoporphyrin
4
Q
ALAS requires cofactor ___
A
B6
5
Q
___ converts ALA to porphobilinogen
A
ALAD
6
Q
___ attaches protoporphyrin to Fe to create heme
A
ferrochelatase
7
Q
3 causes of sideroblastic anemia
A
alcoholism
Pb poisoning
B6 deficiency
8
Q
decreased B12 = ___ homocysteine and ___ MMA
A
increased
decreased
9
Q
DAF function
A
inhibits c3 convertase
10
Q
DAF is anchored by ___
A
GPI
11
Q
___ is absent in PNH
A
CD55 (DAF)
12
Q
direct coombs test
A
agglutination when anti-IgG/complement is added
13
Q
indirect coombs test
A
serum added to anti-IgG/complement
