Hemostasis Flashcards
1
Q
where is vWF derived from?
A
WP bodies (endothelial cells)
alpha granules (platelets)
2
Q
what is the first step of primary hemostasis?
A
vasoconstriction (endothelin)
3
Q
what is the linking molecule for platelet aggregation?
A
fibrinogen
4
Q
most common anticoagulation factor
A
VIII
(mixing study to differentiate from hemophilia A)
5
Q
inactivates plasmin
A
a2-antiplasmin
6
Q
increased fibrinogen split products without d dimers
A
plasmin overactivity
7
Q
thrombomodulin function
A
causes thrombin to activate protein C
8
Q
protein C function
A
inactivate factors V and VIII
9
Q
amniotic fluid embolus description
A
squamous cells and keratin debris
