Rat Diseases Flashcards

1
Q

What is the causative agent of pseudotuberculosis in the rat and causes abscesses in the lungs, liver,kidney, and skin

A

Corynebacterium kuscheri

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2
Q

Describe the appearance of C. kuscheri on gram stain

A

G+ rod in “Chinese letter” formation

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3
Q

Describe the gram stain appearance of Clostridium piliforme, what disease does this bacterium cause?

A

G- spore forming bacillus that causes Tyzzer’s dz

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4
Q

Clinical signs of Pasteurella pneumotropica in the rat?

A

Often asymptomatic may cause conjunctivitis, metritis, mastitis

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5
Q

What is the causative agent of rat bite fever?

A

Streptobacillus moniliformis

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6
Q

Name 3 Helicobacter species that can be found in the rat

A

H. muridarum, H. trogontum, H. bilis

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7
Q

This bacterium can be found near respiratory cilia in rats and coinfection with Mycoplasma result in suppurative bronchopneumonia

A

Cilia-associated respiratory bacillus

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8
Q

Name the causative agent of murine respiratory mycoplasmosis

A

Mycoplasma pulmonis

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9
Q

Name the causative agent of hemobartonellosis in rats

A

Haemobartonella muris

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10
Q

This common G- commensal is noted for its ability to form biofilms

A

Pseudomonas aeruginosa

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11
Q

If S. moniliformis is detected in a laboratory rat colony it is indicates exposure to …

A

Wild rats

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12
Q

What parasite is associated with rodent hemobartonellosis?

A

Polyplax spinulosa (louse)

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13
Q

Sendai virus is what type of virus? (DNA vs RNA, genus, species)

A

RNA virus, Paramyxovirus parainfluenza 1

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14
Q

True or false: Sendai virus is more pathogenic in rats than mice

A

False, often self-limiting

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15
Q

What viruses have a tropism for salivary glands?

A

Rat Corona Virus (RCV-P and RCV-SDA)

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16
Q

Name the 2 major coronaviruses that effect rats

A
Parker’s rat coronavirus (RCV-P)
Sialodacryoadenitis virus (RCV-SDA)
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17
Q

Name two viral rat diseases that can be controlled by allowing them to “burn out”

A

Rat Corona virus and Sendai virus

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18
Q

What viral agents can be an infectious cause of corneal opacities and ulcers in juvenile rats

A

Rat corona virus

19
Q

Name 3 parvoviruses that affect rats

A

Kilham’s rat virus (RV), Toolan’s H1, and rat parvovirus (RPV)

20
Q

What type of nucleic acids do parvoviruses have (RNA? DNA? SS? DS?)

A

SS-DNA

21
Q

Name two paramyxoviruses that can affect rats

A

Sendai virus and Pneumonia virus of mice

22
Q

What family and genus does Hantavirus belong to?

A

Genus Hantavirus and family Bunyaviridae

23
Q

What laboratory rodent species can be a reservoir for the Hantavirus that causes pulmonary syndrome

A

Cotton rat (Sigmodon hispudus)

24
Q

Name the pathogen: This microsporidian pathogen causes clinical clinical signs in rabbits but is clinically silent and rare in rats

A

Encephalitozoan cuciculi

25
Q

What is the primary differential for E. cuniculi in a rat and how can you differentiate between the two?

A

E. cuniculi, 1x2 μm, stain well with Gram and poorly with HE

T. gondii, 2x4 μm, stain well with HE and poorly with Gram

26
Q

Name 2 GI flagellates in rats

A

Spironucleus muris

Giardia muris

27
Q

Name the commensal GI amoeba of rats, mice, and hamsters

A

Entamoeba muris

28
Q

Name 3 oxyurid nematodes that can affect rats, which of theses is the most common?

A

Syphacia muris (most common)
Syphacia obvelata
Aspicularis tetraptera

29
Q

How long is the lifecycle of Syphacia muris?

A

11-15 days

30
Q

Where are Syphacia eggs deposited?

A

Perianal area

31
Q

How long is the life cycle of Aspicularis tetraptera?

A

23-25 days

32
Q

Where are Aspicularis eggs deposited?

A

Passed in feces

33
Q

How can Syphacia eggs and Aspicularis eggs be differentiated on light microscopy?

A

Syphacia- flatted on one side

Aspicularis- bilaterally symmetrical “football”

34
Q

Name the nematode that can be found in the urinary bladder of rats

A

Tricosomoides crassicauda

35
Q

Name thegastric nematode that can cause gastric tumors in rats

A

Gongylonema neoplasticum

36
Q

Name two cestodes of lab rats

A

Hymenolepis dimenuta
Rodentolepis nana (called Hymenolepis nana in the blue book)
Taenia taeniaformis larva (cysts) may also be seen in rats

37
Q

What is the most likely ectoparasite to be encountered in the laboratory rat?

A

Radfordia ensifera

38
Q

Name the causative agent of pediculosis in the laboratory rat?

A

Polypax spinulosa

39
Q

What diagnostic should be performed when a Polypax spinulosa infestation is detected to assess for a common coinfection

A

Blood smears for Haemobartonella muris

40
Q

Name that rat pathogen: This fungus is present in immunocompetent rats and causes pneumonitis in immunocompromised rats

A

Pneumocystis carinii

41
Q

Common age-related kidney disease in the rat

A

Chronic progressive nephropathy

42
Q

Large granular lymphocytic leukemia is prevelent in which rat strain

A

Fischer 344 rats

43
Q

Classifiaction of most pituitary tumors in the rat

A

Chromophobe adenomas