Rare cancers Flashcards
What is a rare cancer classified as?
6 in every 100,000
What is a less common cancer classified as?
12 in every 100,000
What mortality rate does rare and less common cancers have?
50%
How many people with a rare or less common cancer die within 5-years?
26,000 (50%)
What is a multiple myeloma?
Cancer of the plasma cells. Excessive dysfunctional plasma cells in circulation
What are myeloma defining events?
Calcium: 60% plasma cells in the bone marrow
Renal and anaemia: Kappa/lambda light chain ratio >100
Bone lesions: MRI lesions >1 focal lesion
What are some main presentations of multiple myeloma?
Bony lesions Fatigue Blood counts (anaemia, thrombocytopenia, infection) Neuropathy Malnutrition
What is the most common thing patients want in a study that looked at multiple myeloma patients?
Low-cost exercise program
What are some absolute contraindications to exercise in cancer patients?
Unstable bony metastasis New pain Uncontrolled pain Anaemia Thrombocytopenia Fever New chest pain
What are some relative contraindications to exercise in cancer patients?
Neutropenia
Cachexia
Fatigue
GI upset - vomiting, diarrhoea
What is the average VO2max in multiple myeloma patients?
17.5ml/kg/min
Multiple myeloma patients have less than? 6MWT
500m