RAPIDLY GROWING SPECIES Flashcards
- M. abscessus subsp. abscessus (formerly M. abscessus), M. chelonae, and M. fortuitum
MYCOBACTERIUM CHELONAE– MYCOBACTERIUM ABSCESSUS GROUP
been associated with a variety of infections of the skin, lungs, bone, central nervous system, and prosthetic heart valves
- M. chelonae
seen in patients with cystic fibrosis (CF)
- M. abscessus
important reservoir
- tap water
- positive 3-day arylsulfatase test, no reduction of nitrate, and growth on MacConkey agar without crystal violet
MYCOBACTERIUM FORTUITUM GROUP
- M. fortuitum, M. peregrinum, and an unnamed third species.
- Isolated from water, soil, and dust
MYCOBACTERIUM FORTUITUM GROUP
- Associated with localized cutaneous infections
MYCOBACTERIUM FORTUITUM GROUP
- Middlebrook 7H11 agars after 1 to 2 days of incubation colonies with branching
MYCOBACTERIUM FORTUITUM GROUP
- Filamentous extensions and rough colonies with short aerial hyphae
MYCOBACTERIUM FORTUITUM GROUP
- Pleomorphic, ranging from long and tapered to short, thick rods partially acid-fast
MYCOBACTERIUM FORTUITUM GROUP
- Positive 3-day arylsulfatase test and
reduction of nitrate
MYCOBACTERIUM FORTUITUM GROUP
M. smegmatis and M. goodie.
MYCOBACTERIUM SMEGMATIS GROUP
been implicated in rare cases of pulmonary, skin, soft tissue, and bone infections.
- M. smegmatis
- Colonies appearing on egg medium after 2 to 4 days are usually rough, wrinkled, or coarsely folded; smooth, glistening, butyrous colonies may also be seen
MYCOBACTERIUM SMEGMATIS GROUP
- Cells are long and tapered or short rods with irregular acid fastness. Occasionally rods are curved with branching or Y-shaped forms; swollen, with deeper staining, beaded, or ovoid forms are sometimes seen.
MYCOBACTERIUM SMEGMATIS GROUP
- Negative arylsulfatase reaction, positive iron uptake, ability to reduce nitrate, and growth in the presence of 5% NaCl and on MacConkey agar without crystal violet
MYCOBACTERIUM SMEGMATIS GROUP
- Causative agent of Hansen disease (leprosy), an infection of the skin, mucous membranes, and peripheral nerves
MYCOBACTERIUM LEPRAE
- The two major forms of the disease OF Mycobacterium leprae
tuberculoid leprosy (localized & benign) and
lepromatous leprosy (disseminated & malignant)
include skin lesions and nerve involvement that can produce areas with loss of sensation.
- Symptoms of tuberculoid leprosy
if untreated, life-threatening
- Patients with lepromatous leprosy
o It is characterized by skin lesions and progressive, symmetric nerve damage.
o Lesions of the mucous membranes of the nose may lead to destruction of the cartilaginous septum, resulting in nasal and facial deformities
lepromatous leprosy
