NON-TUBERCULOUS MYCOBACTERIA Flashcards
Most common, rapidly
growing mycobacteria
that are associated with
localized cutaneous and
soft tissue infections
MYCOBACTERIUM FORTUITUM
- Microscopy: Pleomhorpic–long to short, thick rods
MYCOBACTERIUM FORTUITUM
- Old cultures: partially AFB
MYCOBACTERIUM FORTUITUM
branching and filamentous with aerial hyphae
MB7H11 OF MYCOBACTERIUM FORTUITUM
growth in media without CRYSTAL VIOLET
MAC OF MYCOBACTERIUM FORTUITU
- Associated with cutaneous infections in immunocompromised persons
MYCOBACTERIUM CHELONAE
- Exhibits greater resistance to
antimicrobial agents
MYCOBACTERIUM CHELONAE
- Microscopy: Strongly acid-fast with
pleomorphism in young cultures
MYCOBACTERIUM CHELONAE
- Culture: Rough to smooth, non-pigmented and have no filamentous branching
MYCOBACTERIUM CHELONAE
- MAC: growth without crystal violet
MYCOBACTERIUM CHELONAE
Reservoir of MYCOBACTERIUM ABSCESSUS SUBSP. ABSCESSUS
: Tap water
- Related infection: Chronic lung disease and Otitis media
MYCOBACTERIUM ABSCESSUS SUBSP. ABSCESSUS
MAC –exhibit growth in a medium without CRYSTAL VIOLET
MYCOBACTERIUM ABSCESSUS SUBSP. ABSCESSUS
(+) 3-day arylsulfatase; (-) Nitrate
biochemical test of MYCOBACTERIUM ABSCESSUS SUBSP. ABSCESSUS
- Related infections: Pulmonary, skin and bone infections
MYCOBACTERIUM SMEGMATIS
(-) 3-day arylsulfatase; (+) Nitrate reduction
biochemical test of MYCOBACTERIUM SMEGMATIS
- Microscopy: Long and tapered rods with partial acid-fastness; maybe beaded or ovoid in form
MYCOBACTERIUM SMEGMATIS
smooth or rough
MB7H10 of MYCOBACTERIUM SMEGMATIS
–exhibit growth in a medium without CRYSTAL VIOLET
o Culture: MAC of MYCOBACTERIUM SMEGMATIS
- Chronic skin disease, mucous membrane and nerve tissue
MYCOBACTERIUM LEPRAE
- Not considered contagious disease
MYCOBACTERIUM LEPRAE
- MOT: Person to person contact through inhalation (nasal secretions), Contact with infected skin, arthropod bites and ingestion of breast milk and transplacental transmission for infants
MYCOBACTERIUM LEPRAE
Tuberculoid (localized & benign) and
Lepromatous Leprosy (disseminated & malignant)
Forms of M leprae
Rod shaped and exhibit “cigar- pocket” or “pocket-fence
MYCOBACTERIUM LEPRAE
Fernandez and Mitzuda Reaction
Skin test for M. leprae
- Well demarcated, dry patch
TUBERCULOID LEPROSY ((TT)
- Minimal disfigurement
o No leonine facies
o No claw-shaped hands
o No pendulous earlobes
TUBERCULOID LEPROSY ((TT)
Good immune response (high resistance)
TUBERCULOID LEPROSY ((TT)
- Disfigurement is there
o Leonine facies
Lepromatous Leprosy
- Disfigurement is there
o Leonine facies
o Claw-shaped hands
o Pendulous ear lobes
o Saddle nose
LEPROMATOUS LEPROSY (LL)
- Suppressed (low resistance)
LEPROMATOUS LEPROSY (LL)