NONTUBERCULOSIS MYCOBACTERIA Flashcards
1
Q
- Slowly Growing Species
A
NONTUBERCULOUS MYCOBACTERIA
2
Q
part of the Mycobacterium avium complex (MAC).
A
- Mycobacterium avium and M. intracellulare
3
Q
o Also includes M. avium subsp. paratuberculosis and M. avium subsp. silvaticum
A
part of the Mycobacterium avium complex (MAC)
4
Q
- environmental saprophytes and have been recovered from soil, water, house dust, and other environmental sources
A
MYCOBACTERIUM AVIUM COMPLEX
5
Q
a cause of disease in poultry and swine
A
MYCOBACTERIUM AVIUM COMPLEX
6
Q
- Zoonotic microorganisms
A
MYCOBACTERIUM AVIUM COMPLEX
7
Q
- the cells are short, coccobacillary, and uniformly stained, without beading or banding
A
MYCOBACTERIUM AVIUM COMPLEX
8
Q
- production of a heat-stable catalase and the ability to grow on media containing 2μg/ mL of T2H
A
MYCOBACTERIUM AVIUM COMPLEX
9
Q
- Causative agent of Johne disease, an intestinal infection occurring as a chronic diarrhea in cattle, sheep, goats, and other ruminants
A
MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS
10
Q
- very slow growth rate (3 to 4 months
A
MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS
11
Q
- Needs mycobactin-supplemented medium for primary isolation.
A
MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS
12
Q
- cause of disseminated infections in patients with AIDS * enteritis and genital and soft tissue infections
A
13
Q
- Middlebrook 7H11 agar supplemented with mycobactin
A
14
Q
- heat-stable catalase, pyrazinamidase, and urease
A
15
Q
- Submandibular lymphadenitis, subcutaneous nodules, painful swellings, ulcers progressing to abscesses, and draining fistulas are often the clinical manifestations
A
16
Q
- A unique characteristic of this organism is its requirement for hemoglobin or hemin for growth.
A
17
Q
- Chocolate (CHOC) agar, Mueller-Hinton agar with 5% Fildes enrichment, and Löwenstein- Jensen (LJ) medium containing 2% ferric ammonium citrate.
A
18
Q
- Optimal growth temperature is 28° C to 32° C; little or no growth occurs at 37° C. cells are strongly acid-fast, short, occasionally curved bacilli without banding or beading, and arranged in tight clusters or cords
A
19
Q
under group III
A
20
Q
strains have been isolated from
water
A
21
Q
- Infections are not normally considered contagious from person to person
A
22
Q
- Susceptible to rifampin and ethambutol
A
23
Q
partially resistant to isoniazid and streptomycin
A
24
Q
resistant to pyrazinamide
A
25
* A multidrug regimen of isoniazid, rifampin, and ethambutol is
currently recommended
26
* Long rods with distinct crossbanding
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* Colonies appear smooth to rough, with characteristic wavy edges and dark centers when grown on Middlebrook 7H10 agar
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Colonies are photochromogenic
29
* With prolonged exposure to light, most strains form dark red crystals of B-carotene on the surface of and inside the colony
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* strongly catalase-positive
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* hydrolyze Tween 80 in 3 days
*
32
strong nitrate reduction
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* Pyrazinamidase production
34
* Under Group I
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* Chronic pulmonary disease and cervical lymphadenitis
36
* Resistant to isoniazid, streptomycin, p- aminosalicylic acid, and rifampin
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susceptible to ethambutol and cycloserine.
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* Short coccobacillus without cross bands on acid- fast–stained smears.
39
* Colonies are smooth glistening, and opaque, with dense centers
40
* Cervical lymphadenitis in children
* Group II
MYCOBACTERIUM SCROFULACEUM
41
* Isolated from the lymph nodes of monkeys
MYCOBACTERIUM SIMIAE
42
* Colonies on Middlebrook 7H10 agar are thin, transparent or tiny, and filamentous
* Group I
MYCOBACTERIUM SIMIAE
43
rare cause of mycobacteriosis, also referred to as Buruli ulcer
* Acid-fast cells are long, without beading or crossbanding
* Group III
44
has been implicated in
diseases of fish and isolated from aquariums
MYCOBACTERIUM MARINUM
45
* Cutaneous infections in humans occur when traumatized skin comes into contact with salt water or inadequately chlorinated fresh water containing the organism.
MYCOBACTERIUM MARINUM
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* Susceptible to rifampin and ethambutol
MYCOBACTERIUM MARINUM
47
resistant to isoniazid and pyrazinamide
MYCOBACTERIUM MARINUM
48
partially resistant or intermediate to streptomycin
MYCOBACTERIUM MARINUM
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are moderately long to long rods with cross barring.
MYCOBACTERIUM MARINUM CELLS
50
* Colonies grown or exposed to light develop a deep yellow color
MYCOBACTERIUM MARINUM CELLS
51
* Growth is optimum at incubation temperatures of
28° C to 32° C
52
* None reduces nitrate or produces heat-stable catalase
MYCOBACTERIUM MARINUM CELLS
53
* The organisms hydrolyze Tween 80 and produce urease and pyrazinamidase.
* Group I
MYCOBACTERIUM MARINUM CELLS
54
* Recovered from hot and cold water taps (including water storage tanks of hospitals) and birds (hotspings)
MYCOBACTERIUM XENOPI
55
* Susceptible to the quinolones (ciprofloxacin, ofloxacin);
MYCOBACTERIUM XENOPI
56
some isolates are susceptible to vancomycin, erythromycin, or cefuroxime
MYCOBACTERIUM XENOPI
57
* Colonies on Middlebrook 7H10 agar are small, with dense centers and filamentous edges.
MYCOBACTERIUM XENOPI
58
reveals distinctive round colonies with branching and filamentous extensions; aerial hyphae are usually seen in rough colonies.
* Cornmeal-glycerol agar
59
* Young colonies grown on cornmeal agar have a bird’s nest appearance, with characteristic sticklike projections.
* Group II
MYCOBACTERIUM XENOPI
