NONTUBERCULOSIS MYCOBACTERIA Flashcards

1
Q
  • Slowly Growing Species
A

NONTUBERCULOUS MYCOBACTERIA

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2
Q

part of the Mycobacterium avium complex (MAC).

A
  • Mycobacterium avium and M. intracellulare
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3
Q

o Also includes M. avium subsp. paratuberculosis and M. avium subsp. silvaticum

A

part of the Mycobacterium avium complex (MAC)

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4
Q
  • environmental saprophytes and have been recovered from soil, water, house dust, and other environmental sources
A

MYCOBACTERIUM AVIUM COMPLEX

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5
Q

a cause of disease in poultry and swine

A

MYCOBACTERIUM AVIUM COMPLEX

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6
Q
  • Zoonotic microorganisms
A

MYCOBACTERIUM AVIUM COMPLEX

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7
Q
  • the cells are short, coccobacillary, and uniformly stained, without beading or banding
A

MYCOBACTERIUM AVIUM COMPLEX

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8
Q
  • production of a heat-stable catalase and the ability to grow on media containing 2μg/ mL of T2H
A

MYCOBACTERIUM AVIUM COMPLEX

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9
Q
  • Causative agent of Johne disease, an intestinal infection occurring as a chronic diarrhea in cattle, sheep, goats, and other ruminants
A

MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS

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10
Q
  • very slow growth rate (3 to 4 months
A

MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS

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11
Q
  • Needs mycobactin-supplemented medium for primary isolation.
A

MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS

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12
Q
  • cause of disseminated infections in patients with AIDS * enteritis and genital and soft tissue infections
A
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13
Q
  • Middlebrook 7H11 agar supplemented with mycobactin
A
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14
Q
  • heat-stable catalase, pyrazinamidase, and urease
A
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15
Q
  • Submandibular lymphadenitis, subcutaneous nodules, painful swellings, ulcers progressing to abscesses, and draining fistulas are often the clinical manifestations
A
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16
Q
  • A unique characteristic of this organism is its requirement for hemoglobin or hemin for growth.
A
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17
Q
  • Chocolate (CHOC) agar, Mueller-Hinton agar with 5% Fildes enrichment, and Löwenstein- Jensen (LJ) medium containing 2% ferric ammonium citrate.
A
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18
Q
  • Optimal growth temperature is 28° C to 32° C; little or no growth occurs at 37° C. cells are strongly acid-fast, short, occasionally curved bacilli without banding or beading, and arranged in tight clusters or cords
A
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19
Q

under group III

A
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20
Q

strains have been isolated from
water

A
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21
Q
  • Infections are not normally considered contagious from person to person
A
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22
Q
  • Susceptible to rifampin and ethambutol
A
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23
Q

partially resistant to isoniazid and streptomycin

A
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24
Q

resistant to pyrazinamide

A
25
Q
  • A multidrug regimen of isoniazid, rifampin, and ethambutol is
A

currently recommended

26
Q
  • Long rods with distinct crossbanding
A
27
Q
  • Colonies appear smooth to rough, with characteristic wavy edges and dark centers when grown on Middlebrook 7H10 agar
A
28
Q

Colonies are photochromogenic

A
29
Q
  • With prolonged exposure to light, most strains form dark red crystals of B-carotene on the surface of and inside the colony
A
30
Q
  • strongly catalase-positive
A
31
Q
  • hydrolyze Tween 80 in 3 days
    *
A
32
Q

strong nitrate reduction

A
33
Q
  • Pyrazinamidase production
A
34
Q
  • Under Group I
A
35
Q
  • Chronic pulmonary disease and cervical lymphadenitis
A
36
Q
  • Resistant to isoniazid, streptomycin, p- aminosalicylic acid, and rifampin
A
37
Q

susceptible to ethambutol and cycloserine.

A
38
Q
  • Short coccobacillus without cross bands on acid- fast–stained smears.
A
39
Q
  • Colonies are smooth glistening, and opaque, with dense centers
A
40
Q
  • Cervical lymphadenitis in children
  • Group II
A

MYCOBACTERIUM SCROFULACEUM

41
Q
  • Isolated from the lymph nodes of monkeys
A

MYCOBACTERIUM SIMIAE

42
Q
  • Colonies on Middlebrook 7H10 agar are thin, transparent or tiny, and filamentous
  • Group I
A

MYCOBACTERIUM SIMIAE

43
Q

rare cause of mycobacteriosis, also referred to as Buruli ulcer

A
  • Acid-fast cells are long, without beading or crossbanding
  • Group III
44
Q

has been implicated in
diseases of fish and isolated from aquariums

A

MYCOBACTERIUM MARINUM

45
Q
  • Cutaneous infections in humans occur when traumatized skin comes into contact with salt water or inadequately chlorinated fresh water containing the organism.
A

MYCOBACTERIUM MARINUM

46
Q
  • Susceptible to rifampin and ethambutol
A

MYCOBACTERIUM MARINUM

47
Q

resistant to isoniazid and pyrazinamide

A

MYCOBACTERIUM MARINUM

48
Q

partially resistant or intermediate to streptomycin

A

MYCOBACTERIUM MARINUM

49
Q

are moderately long to long rods with cross barring.

A

MYCOBACTERIUM MARINUM CELLS

50
Q
  • Colonies grown or exposed to light develop a deep yellow color
A

MYCOBACTERIUM MARINUM CELLS

51
Q
  • Growth is optimum at incubation temperatures of
A

28° C to 32° C

52
Q
  • None reduces nitrate or produces heat-stable catalase
A

MYCOBACTERIUM MARINUM CELLS

53
Q
  • The organisms hydrolyze Tween 80 and produce urease and pyrazinamidase.
  • Group I
A

MYCOBACTERIUM MARINUM CELLS

54
Q
  • Recovered from hot and cold water taps (including water storage tanks of hospitals) and birds (hotspings)
A

MYCOBACTERIUM XENOPI

55
Q
  • Susceptible to the quinolones (ciprofloxacin, ofloxacin);
A

MYCOBACTERIUM XENOPI

56
Q

some isolates are susceptible to vancomycin, erythromycin, or cefuroxime

A

MYCOBACTERIUM XENOPI

57
Q
  • Colonies on Middlebrook 7H10 agar are small, with dense centers and filamentous edges.
A

MYCOBACTERIUM XENOPI

58
Q

reveals distinctive round colonies with branching and filamentous extensions; aerial hyphae are usually seen in rough colonies.

A
  • Cornmeal-glycerol agar
59
Q
  • Young colonies grown on cornmeal agar have a bird’s nest appearance, with characteristic sticklike projections.
  • Group II
A

MYCOBACTERIUM XENOPI