Rapid Review - Set 05 - Sheet1

Question 1

Swollen, hard, painful finger joints

Answer 1

Osteoarthritis (PIP: Bouchard’s nodes; DIP: Heberden’s nodes)

Question 2

Systolic ejection murmur (crescendo-decrescendo)

Answer 2

Aortic Valve Stenosis

Question 3

Thyroid and parathyroid tumors, pheochromocytoma

Answer 3

MEN 2A (autosomal dominant RET mutation)

Question 4

Thyroid tumors, pheochromocytoma, ganglioneuromatosis

Answer 4

MEN 2B (autosomal dominant RET mutation)

Question 5

Toe extension/fanning upon plantar scrape

Answer 5

Babinski sign (UMN lesion)

Question 6

Unilateral facial drooping involving forehead

Answer 6

LMN CN VII palsy (Facial n.)

Question 7

Urethritis, conjunctivitis, arthritis in a male

Answer 7

Reactive arthritis (associated with HLA-B27) “Reiter’s Syndrome”

Question 8

Vascular birthmark (port-wine stain)

Answer 8

Hemangioma (benign, but associated with Sturge-Weber syndrome)

Question 9

Vomiting blood following gastroesophageal lacerations

Answer 9

Mallory-Weiss syndrome (alcoholic and bulmic patients)

Question 10

Weight loss, diarrhea, arthritis, fever, adenopathy

Answer 10

Whipple’s disease (Tropheryma whipplei)

Question 11

“worst headache of my life”

Answer 11

Subarachnoid hemorrhage

Question 12

Anticentromere Antibodies

Answer 12

Scleroderma (CREST)

Question 13

Antidesmoglein (epithelial) Antibodies

Answer 13

Pemphigus vulgaris (blistering)

Question 14

Anti-glomerular basement membrane Antibodies

Answer 14

Goodpasture’s Syndrome (glomerulonephritis and hemoptysis)

Question 15

Antihistone Abs

Answer 15

Drug-induced SLE (hydralazine, isoniazid, phenytoin, procainamide)

Question 16

Anti-IgG Abs

Answer 16

Rheumatoid Arthritis (systemic inflammation, joint pannus, boutonniere deformity)

Question 17

Antimitochondrial Abs (AMAs)

Answer 17

Primary biliary cirrhosis (female, cholestasis, portal HTN)

Question 18

Antineutrophil Cytoplasmic Abs (ANCAs)

Answer 18

Vasculitis (c-ANCA: granulomatosis with polyangiitis [Wegener’s]; p-ANCA: microscopic polyangiitis, Churg-Strauss syndrome)

Question 19

Antinuclear Abs (ANAs: anti-Smith and anti-dsDNA)

Answer 19

SLE (type III hypersensitivity)

Question 20

Antiplatelet Abs

Answer 20

Idiopathic Thrombocytopenic purpura

Question 21

Anti-topoisomerase Abs

Answer 21

Diffuse Systemic Scleroderma

Question 22

Anti-transglutaminase/Anti-Gliadin/Anti-Endomysial Abs

Answer 22

Celiac disease (diarrhea, distention, weight loss)

Question 23

“Apple core” lesion on abdominal x-ray

Answer 23

Colorectal ca. (usually left sided)

Question 24

Azurophilic peroxidase + granular inclusions in granulocytes and myeloblasts

Answer 24

Auer Rods (Acute myelogenous leukemia, especially the promyelocytic M3 type)

Question 25

Bacitracin Sensitive bacteria

Answer 25

Strep pyogenes (Group A)

Question 26

Bacitracin Resistant bacteria

Answer 26

Strep agalactiae (Group B)

Question 27

"Bamboo spine" on x-ray

Answer 27

Ankylosing spondylitis (chronic inflammatory arthritis: HLA-B27)