Rapid Review - Equations Flashcards
Sensitivity
TP/ (TP + FN)
Specificity
TN/ (TN + FP)
Positive Predictive Value
TP/ (TP + FP)
Negative Predictive Value
TN/ (TN + FN)
Odds Ratio (for case control studies)
A/C / B/D = AD/BC
Relative risk
[A/(A+B)] / [C/(C+D)]
Attributable risk
[A/(A+B)] - [C/(C+D)]
Number needed to treat
1/absolute risk reduction
Number needed to harm
1/attributable risk
BMI
weight in kg/(height in meters^2)
Hardy-Weinberg equilibrium
p^2 + 2pq + q^2 = 1
p + q = 1
Volume of Distribution
Vd = amount of drug in body/ plasma drug concentration
Half life
(0.7xVd)/ CL
Clearance
rate of elimination of drug/ plasma drug concentration
Vd * Ke (elimination constant)
Loading Dose
Cp * (Vd/F)
plasma concentration * volume of distribution/bioavailability
Maintenance Dose
Cp * (CL/F)
plasma concentration * clearance/bioavailability
Cardiac Output
SV * HR or
Rate of O2 consumption/ (Arterial - Venous O2 content)
Mean Arterial Pressure
CO * TPR or
2/3 diastolic + 1/3 systolic
Stroke volume
CO/HR or
EDV - ESV
Ejection fraction
SV/ EDV or
(EDV - ESV)/EDV
Resistance
change in P/Q = change in pressure/flow or
8nl/(pir^4) [n=viscosity]
Net Filtration Pressure
[(Pc-Pi)] - (Pi-c - Pi-i)
Kf(Pnet)
Renal clearance
CL = Urine concentration * Volume/Px
GFR
Uinulin * V/Pinulin = Cinulin
Kf [(Pressure GC - Pressure Bowman space) - (Pi GC - Pi BS)]
