Random Peds stuff Flashcards

1
Q

What are the complications of Kawasaki disease?

A

1) coronary artery aneurysms, 2) myocardial infarction and ischemia

Dilated arteries are prone to thrombotic occlusion. Risk is higher in those with delayed diagnosis.

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2
Q

What is the triad for hereditary spherocytosis?

A

1) hemolytic anemia
2) jaundice
3) splenomegaly

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3
Q

What is the treatment of x-linked agammaglobulinemia

A

immunoglobulin replacement therapy. Prophylactic antibiotics if severe.

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4
Q

Guillian-Barre syndome (GBS)

A

acute, immune-mediated polyneuropathy accompanied by ascending muscle weakness and areflexia. Distal paresthesias are common

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5
Q

What is choanal atresia?

A

congenital nasal malformation caused by failure of the posterior nasal passage to canalize completely leaving either a bony or membranous obstruction. Narrowing at the level of the pterygoid plate in the posterior nasal cavity. Can be found isolated or as part of the CHARGE syndrome

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6
Q
  • sudden intermittent abdominal pain
  • currant jelly stools (bloody stool)
  • sausage-shaped abdominal mass
  • lethargy or altered mental status
A

intussusception

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7
Q

what is oligohydramnios?

A

deficiency of amniotic fluid

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8
Q

What bacteria causes hemolytic uremic syndrome ?

A

infection with shiga toxin by E.coli (O157:H7)

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9
Q

what is the inheritance pattern for hereditary spherocytosis?

A

autosomal dominant mutation of the ankyrin gene (decreased ankyrin in the red blood cell membrane)

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10
Q
  • low-grade fever
  • maculopapular rash with rapid cephalocaudal spread
  • posterior auricular and suboccipital lymphadenopathy
A

Rubella. Can also present with arthralgia and arthritis that can persist after the rash resolves.

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11
Q

What is the gold standard for diagnosis for DMD?

A

genetic testing showing deletion of the dystrophin gene on Xp21

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12
Q

What test should be done on a patient with kawasaki disease?

A

echocardiography at time of diagnosis and repeated 6-8 weeks later to assess change

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13
Q

What is the treatment of obsessive-compulsive disorder in children ?

A

SSRIs and cognitive-behavioral psychotherapy

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14
Q

What is the definitive treatment for choanal atresia?

A

repairing the obstruction with surgery or endoscopy

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15
Q

what is the typical age for stranger anxiety?

A

6-2 years

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16
Q

at what age can a child build a tower with 6 cubes?

A

2 years

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17
Q

What is the most common muscular dystrophy in children?

A

Duchenne muscular dystrophy (DMD)

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18
Q

What is the classic triad of hemolytic uremic syndrome?

A

1) microangiopathic hemolytic anemia (anemia and schistocytes)
2) thrombocytopenia
3) acute kidney injury (poor urine output, edema, elevated creatinine and BUN)

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19
Q

pretend play is a developmental milestone of what age?

A

18 months

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20
Q

how is a diagnosis of PUV confirmed?

A

1) voiding cystourethrogram (an x-ray study of bladder and urethra using contrast to visual bladder and also done while voiding) and
2) cystoscopy (examine bladder lining and urethra with camera)

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21
Q

3-hour-old boy with cyanosis. Cyanotic and tachypneic at rest but turns pink when cries. Cyanosis worsens when feeding. What is the most likely diagnosis?

A

choanal atresia

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22
Q

What are the classic findings on prenatal U/S for a baby with posterior urethral valves?

A

1) bladder distension
2) bilateral hydroureters
3) bilateral hydronephrosis

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23
Q

how is the diagnosis of choanal atresia confirmed?

A

CT scan

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24
Q

A congenital abnormality in which the penile urethra opens on the ventral surface of the penis rather than the tip

A

hypospadias - able to urinate but difficulty controlling urinary stream

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25
Q

What does henoch-schonlein purpura present with?

A
  • purpura
  • arthritis
  • renal disease
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26
Q

an atretic duodenum can lead to polyhydramnios or oligohydramnios?

A

polyhydramnios because obstructs amniotic fluid clearance.

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27
Q

When can a child balance and hop on 1 foot?

A

4 years

28
Q

What is X-linked agammaglobulinemia (XLA) a.k.a bruton agammaglobulinemia

A

Caused by a defect in tyrosine kinase that prevents the development of mature B cells.

29
Q

What is the treatment for ADHD?

A

1) stimulants (methylphenidate, amphetamines)
2) nonstimulants (atomoxetine, alpha-2 adrenergic agonists)
3) behavioural therapy

30
Q

What is the clinical presentation of laryngomalacia?

A

inspiratory stridor that worsens when supine and peaks at age 4-8 months

31
Q

How do most patients with wilms tumor present?

A

at age 2-5 years with a large, palpable flank mass but no other symptoms

32
Q

What is the CHARGE syndrome?

A
C - coloboma
H - Heart defects
A - Atresia choanae
R - Retardation of growth/development
G - genito-urinary anomalies 
E - ear abnormalities/deafness
33
Q

What is the difference in indication for ordering a spirometry test vs a peak flow meter test?

A

Spirometry - evaluates pulmonary function (FVC, forced expiratory volume in 1 second)

Peak flow meter - assessment of airflow out of the lungs (peak expiratory flow rate) Less accurate than spirometry

34
Q

What test is used to diagnose Meckel’s diverticulum?

A

Technetium-99m scan to identify ectopic gastric tissue

35
Q

What test is used to determine intussusception if the diagnosis is equivocal?

A

U/S - target sign

36
Q

At what ages does cooperative play occur?

A

4 years

37
Q

What is the most common renal malignancy in childhood?

A

wilms tumor (nephroblastoma)

38
Q

At what age does a child use 2 word phrases

A

2 years

39
Q

during screening for muscular dystrophies, what things are normally elevated?

A

serum creatine phosphokinase and aldolase levels

40
Q

What causes laryngomalacia

A

caused by floppy supraglottic structures that collapse during inspiration.

41
Q

What is the treatment for laryngomalacia ?

A

reassurance for most cases and supraglottoplasty for severe symptoms

42
Q

What is the most important next step in management once a diagnosis of GBS is suspected?

A

spirometry to measure forced vital capacity (gold standard)

43
Q

What is the most common cause of urinary tract obstruction in newborn boys?

A

Posterior urethral valves. Abnormal folds in the distal prostatic urethra obstruct urinary flow.

44
Q

What is kawasaki disease

A

an acute vasculitis of small and medium arteries.

45
Q

How is the diagnosis of laryngomalacia confirmed?

A
  • clinical but confirmed with flexible laryngoscopy for moderate/severe cases
46
Q

What is the treatment for intussusception?

A

1) air or saline enema (u/s guided) - diagnostic and therapeutic
2) surgery for removal of lead point

47
Q

At what age does DMD usually present?

A

age 2-5

48
Q

What is the potter sequence?

A

flat faces, limb deformities, pulmonary hypoplasia due to oligohydramnios.

49
Q

Kawasaki disease features

A

Fever ≥ 5 days, conjunctivitis (bilateral, nonexudative, spares limbus), oral mucosal changes (strawberry tongue, erythema, fissured lips), rash, extremity changes (erythema, deem, desquamation of hands and feet), cervical lymphadenopathy

50
Q

What is the most life-threatening complication in patients with gillian barre syndrome?

A

neuromuscular respiratory failure

51
Q

What is the treatment for hereditary spherocytosis

A

folic acid supplementation, blood transfusions, splenectomy

52
Q

What is the first step in management of choanal atresia

A

placing an orophrangeal airway and orogastric tube feeding

53
Q

at what age can a child use a pincer grasp?

A

12 months

54
Q

a child can run and kick a ball at what developmental age?

A

18 months

55
Q

What are the lab findings for hereditary spherocytosis?

A

increased mean corpuscular hemoglobin concentration, spherocytes on peripheral smear, negative coombs test, increased osmotic fragility , abnormal eosin-5-maleimide binding test.

56
Q

How is amniotic fluid removed by the fetus?

A

fetal swallowing

57
Q

What are the treatment options for PUV?

A

1) PUV ablation

2) urinary diversion

58
Q

What are the 4 categories for developmental milestones?

A

gross motor, fine motor, language, social/cognitive

59
Q

Describe the pathophysiology of Hemolytic Uremic Syndrome

A

systemic vascular endothelial injury –> platelet microthrombi formation –> thrombocytopenia and schistocytes as they flow through small vessels

60
Q

What is anorectal manometry?

A

a test used to analyze the motility and pressure in the distal bowel. Often used to diagnose Hirschsprung disease

61
Q

What is the treatment of kawasaki’s disease?

A

aspirin plus IVIG - intravenous immunoglobulin to reduce systemic inflammation

62
Q

What are the clinical manifestations of x-linked agammaglobulinemia

A
  • recurrent sinopulmonary and gastrointestinal infections after age 6 months (e.g H.influenzae, Strep pneumoniae)
  • absence of lymphoid tissue on examination
63
Q

At what age can a child throw a ball?

A

12 months

64
Q

Henoch-schonlein purpura is associated with what GI complication?

A

intussusception

65
Q

What condition is likely on the differential when a patient presents with bilateral calf pseudohypertrophy and Gower sign ?

A

Duchenne muscular dystrophy