random msa questions Flashcards
what are the three main routes of metastatic spread of cancer?
- lymphatic
- haematogenous
- transcoelomic
give one examples of a cancer which spreads?
colon cancer metastasises to liver
name 2 clinical classifications of tumours:
- benign
- malignant
name two histological classifications of tumours:
- epithelial
- mesenchyme
what are 5 features of benign tumours?
- growth is slow
- growth is non-invasive
- benign tumours do not spread
- do not recur when removed
- tumour margins are not well defined
name 5 features of malignant tumours:
- growth is rapid
- growth is invasive (destroys tissue)
- tumour spreads
- recurrence after excision
- tumour margins are well defined
name two benign tumours are their tissue of origin:
- lipoma = fat tissue
- chondroma = cartilage
name two malignant tumours and their tissue of origin:
- carcinoma = epithelial cells
- lymphoma = bone marrow/blood forming cell
name 4 demographic factors (characteristics of a population, expressed statistically):
- Age
- Sex/gender
- employment status
- postcode
briefly describe the Ingestion phase of feeding:
- movement of food from external environment to internal environment
- accomplished by biting and oral seal
briefly describe stage on of transport in the feeding cycle:
food is gathered on tongue tip and moved to the level of the posterior teeth
briefly describe the mechanical processing phase of the feeding cycle:
- solid foods are broken down and mixed with saliva before swallowing
- moist solid foods need to have fluid removed before transport & swallowing
- food is chewed with premolars and molars
- soft foods are squashed against the hard palate
what occurs in stage two of transport during feeding?
- bolus moved posteriorly by ‘squeeze back’ mechanism
- solid foods moved through fauces to pharyngeal surface of tongue
- ‘seal’ holds liquids at pillars of fauces
what occurs during the swallowing pharyngeal phase of the feeding cycle?
- involuntary movements push bolus through pharynx into oesophagus
- epiglottis seals of larynx preventing food entering the respiratory tract
- UOS relaxes, to allow bolus into the oesophagus and then contracts to counteract backflow
why might ditching occur in an amalgam restoration?
- material is repeatedly stressed for long periods at low stress levels: below elastic limit
- it may flow resulting in permanent deformation
- amalgam then sits proud of surface due to this flow, and is vulnerable to fracture
what can a dentist do, in terms of cavity prep, to avoid ditching in an amalgam restoration?
- remove all caries
- use acid etch and bond
- use a lining material
- lining material helps spread forces down the long axis of the tooth, instead of placing stress on the interface between tooth & restoration
- this reduced stress on the amalgam therefor reducing creep & therefor reducing ditching
what are examples of 4 factors that may contribute to secondary caries in an amalgam restoration?
- microleakage due to no chemical bond between restoration and tooth
- fracture of enamel at margins causing ditching has compromised any seal that was present at the restoration/tooth interface
- poor oral hygiene will prevent removal of plaque
- there is no lining material underlying the amalgam, meaning the dentine has no protection from bacteria and endotoxins
what are 5 risk factors that make someone a high caries risk?
- poor oral hygiene
- poor diet
- xerostomia
- frequency of sugar intake
- susceptible tooth surface (tight contacts, receded gingiva)
how is cystic fibrosis acquired?
it is an inherited disorder
- CFTR gene - chromosome 7
- recessive gene
- both parents must have it
what are the treatment options for a patient suffering with cystic fibrosis?
- physiotherapy
- exercise
- medication
- transplantation
how does cystic fibrosis affect the body?
- inherited gene defect in cell chloride channels
- produces excess sticky mucous
- lungs are congested
- malabsorption of nutrients in the pancreas
how can you test for cystic fibrosis?
- perinatal testing (all children are now screened at birth)
- sweat test (measures salt content of sweat which is higher in CF patients)