Radiology of Lung Cancer and Staging Flashcards

1
Q

What can an opacity of a chest X-ray indicate?

A

Pulmonary nodule

Mass

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2
Q

What should you note about the mediastinal area?

A

Hilar vascular structures well defined

No widening of mediastinum

Central Trachea

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3
Q

What should you look for when examaning the lungs?

A

Compare zones

Between ribs for lung detail

Behind heart

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4
Q

In a chest X ray, what are the systematic review areas?

A

Hila

Lung apices

Behind heart

Behind diaphragm

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5
Q

What clinical history might be indicative of lung cancer?

A
  • Increasing SOB
  • Smoker
  • History of pulmonary fibrosis
  • Recent haemoptysis
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6
Q

What is the next step in diagnosis after a chest X ray?

A

CT

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7
Q

What does a CT tell you about a mass/nodule?

A
  • Size
  • shape
  • border
  • atelectasis
  • density
  • solid vs non-solid

(atelectasis - partial collapse/incomplete lung inflation)

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8
Q

What is a pulmonary mass?

A

Lung opacity over 3 cm

No mediastinal adenopathy (enlargement lymph nodes) or atelectasis

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9
Q

What is a pulmonasry nodule?

A

Lung opacity up to 3cm with no mediastinal adenopathy or atelectasis.

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10
Q

What can a solitary pulmonary nodule be indicative of?

A

Lung cancer - (likely if patient smokes, old age)

Metastasis - (from breast cancer, renal cancer, seminoma, sarcoma)

Benign lung neoplasm, carcinoid, hamartoma

Infection bacterial, tb or fungal

Vascular haematoma, AVM (arteriovenous malformation)

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11
Q

What does TIA stand for?

A

Transient ischaemic attack

Reults in lack of blood and oxygen to brain (mini-stroke)

Symptoms are short and temporary

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12
Q

What do the letters TNM stand for?

A

T - Size and position of tumour

N- nodal involvement

M - Metastasis (yes/no?)

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13
Q

What are the testing techniques to determine the T? (size and position)

A

CT

PETCT

Bronchoscopy - (uses fibre optic endosope)

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14
Q

How is N determined?

A

PET-CT

Mediatinoscopy

CT

EBUS/EUS

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15
Q

How is M determined?

A

PETCT

CT

bone scan

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16
Q

What is EBUS?

A

Endobronchial ultrasound

17
Q

What is the chemical used by a PET scan?

18
Q

Who are PET scans offered to?

A

Patients likely to benefit from treatment (surgery or radical chemo or radiotherapy)

19
Q

What are Tx/T0/Tis tumours?

A

Tx - Primary tumour cannot be assessed

T0 - no evidence of primary tumour

Tis- carcinoma in situ

20
Q

What are tumours labelled T1?

A

T1 ≤ 3cm no main bronchus inv.

Tumour surrounded by lung or visceral pleura

21
Q

What is a T1 (a,b and c tumour?)

A

T1a - minimally invasive adenocarcinoma, less than 1 cm

T1b - less than 2 cm

T1c - less than 3 cm

22
Q

What is the classification of a T2 tumour?

A
  • 3 and 5 cm
  • involves main bronchus, not trachea carina
  • invades visceral pleura
  • Associated with atelectasis or obstructive pneumonitis that extends to hilar, involving part/all lung
23
Q

What is a T2a and T2b tumour?

A

T2a - >3 cm, less than 4cm

T2b - >4 cm, less than 5 cm

24
Q

What is a T3 tumour?

A

5 - 7 cm

Directly invades:

  • Chest wall (including superior sulcus tumours)
  • Phrenic nerve
  • Parietal pericardium

Separate tumour nodules in same lobe as primary

25
What is a T4 tumour?
Greater than 7 cm Invades: * Diaphragm * Mediastinum * Heart * Great vessels * Trachea * Recurrent laryngeal nerve * Oesophagus * Vertebral body * Carina Separate tumour nodules in different ipsilateral lobe
26
What does N0 indicate?
No regional lymph node metastases | (LN - Lymph Node)
27
What does N1 indicate?
Ipsilateral peribronchial hilar intrapulmonary LN
28
What does N2 indicate?
Ipsilateral mediastinal sub carinal
29
What does N3 indicate?
Contralateral mediastinal contralateral hilar scalene supraclavicular
30
What are the common places for lung cancer to metastasise?
Cerebral Skeletal Adrenal Liver
31
What does M0 indicate?
No metastasis
32
What does M1 indicate?
Distant metastasis
33
What does M1a indicate?
Separate tumour nodule in contralateral lobe Pleural/pericardial nodule or malignant pleural/pericardial effusion
34
What does M1b stand for?
Single distant metastasis
35
What does M1c indicate?
Multiple distant metastasis
36
What is the purpose of PET/CT in staging?
Whole body staging (excluding cerebral disease) Discloses metastasis and other pathology Excludes metastasis where structural imaging is abnormal Non-invasive
37
What are the limitations of PET CT?
False negative results False positive results Cost
38
How is tissue diagnosis achieved?
Bronchoscopy and EBUS Percutaneous image guided biopsy