Radiation Safety Flashcards
KERMA
Kinetic energy released per unit mass
The initial large energy transfer involving one atom
Use for radiation with no charge (photos and neutrons)
Kerma K =
Kinetic energy of all charged particles liberated by protons in a small mass, m
1Gy = 1JKg-1
Dose =
Many small energy deposits involving many atoms along the electron track
Energy absorbed from a beam of radiation per unit mass up to material
1Gy = 1JKg-1
Difference between KERMA and absorbed dose is
Electron energy converted to bremsstrahlung radiation
K >D
Organ dose (DT) =
Average absorbed dose or energy over mass of organ
Equivalent dose =
Radiation factors applied to organ dose
Factors the damaging effects of radiation on tissue
More charge = Higher radiation weighting factor
Sv = 1JKg^-1
Radiation waiting factor depends on
Ionisation density tissue produced by the radiation
More charge or mass = ? radiation weighting factor
More charge or mass = Higher radiation weighting facto
XRs, gamma and electrons Wr =1
Protons = 2
Alpha particles = 20
Neutrons = 5-20 depending on energy
Effective dose =
Tissue weighting factors applied to effective dose
W(T) Factors the tissue radiation sensitivity
Also, how easily treatable the radiation harm is
Effective dose =
Gives information on overall risk of stochastic effects
Can be used to compare risk from different types of exposures
Ionising radiation interaction with tissue
Free radicals = chemical damage
Molecular changes = DNA or RNA damage
Sub-cellular and cellular changes =
- tissue effects such as cell death
- Cellular transformation (stochastic effect)
Free radical production
Ionisation of water:
H20 and radiation -> H20+ + e-
H20+ -> H+ + OH
OH is chemically damaging
Tissues at risk
Actively dividing:
Bone marrow
Gonadal germ cells
Intestinal epithelium
Skin
Tissue reactions or deterministic effects
Radiation-induced cell death
Does not occur below the threshold dose = 1% incidence
Threshold doses for acute exposures