Mersey US Flashcards

1
Q
  • Pressure varies along an US wave
  • Pressure is highest at a compression & lowest at a rarefaction
  • Wavelength = distance between corresponding compressions
  • Frequency = number of wavelengths emitted each second
  • Amplitude = increase in pressure at a compression
A
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2
Q

Acoustic Impedance (Z)

  • A measure of how a tissue resists the passage of the US wave
  • Z is affected by the density & compressibility of tissue
  • For any tissue: Z = density x wave speed
  • Z is measured in units of rayl
A
  • NB – Z is independent of the US frequency
  • Bone and PZT crystals have high Z
  • Air & lung have low Z
  • Differences in Z between tissues are important for
    creating reflections (echoes)
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2
Q
  • Wavelength range 0.1-1.0mm in clinical images
  • Audible range of the human ear is 20Hz - 20kHz
  • US imaging uses a frequency range 2-15 MHz
A
  • In US, frequency is inversely proportional to wavelength
    ➢ At 1.5MHz: wavelength = 1.0mm in soft tissue
    ➢ At 15MHz: wavelength = 0.1mm in soft tissue
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3
Q

Speed of Propagation (Wave Speed)

  • Waves speed depends on the stiffness or
    compressibility of the tissue or medium
  • Wave speed, c = frequency x wavelength
  • US machines assume the waves travel at 1540m/s in the patient
  • Speed of propagation varies for different tissues
    ➢ Bone 4000 ms-1
    ➢ Fat 1450 ms-1
    ➢ Lung 600 ms-1
A

Wave speed is independent of the US frequency

NEED TO KNOW FOR EXAM

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4
Q

Interactions of US with Tissue

There are 4 basic interactions of US radiation with tissue:
* Reflection – partial reflection can occur at boundaries of 2 dissimilar tissues.
* Scattering – structures smaller than the wavelength of the beam scatter US radiation in all directions

A
  • Refraction – change in direction of US wave when striking a boundary of 2 tissues obliquely
  • Absorption – US energy is converted into heat as it passes through tissue
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5
Q

Specular Reflection

  • Specular reflection occurs at large, smooth boundaries between
    tissues where there is a change in acoustic impedance
  • Incident wave is partially reflected
  • The reflected ‘echo’ is weaker than the incident wave
  • The incident wave is transmitted with reduced amplitude
  • The transmitted wave can create further echoes
A
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6
Q
  • When the incident beam strikes the boundary obliquely specular
    reflection still occurs
  • The angle of reflection = angle of incidence
  • The intensity of the reflected wave is still reduced
A
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7
Q

Scattering

  • Structures < wavelength cause scattering
  • Very weak echoes produced in all directions
  • Wavelength depends on frequency, so scattering will also depend on frequency
  • At 1.5MHz, scattering occurs from objects < 1mm
  • At 15MHz, scattering occurs from objects < 0.1mm
A
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7
Q

Specular reflection – echo strength

  • The intensity of the reflected wave (with respect to the incident wave) depends on the difference in acoustic impedance between the 2 tissues (Z1 & Z2)
  • Relative echo strength is independent of US frequency
A
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8
Q

Diffuse Reflection

  • Diffuse reflection occurs if the reflecting surface interface isrough or has undulations that are smaller than the wavelength of the radiation
  • Multiple reflected waves are generated & emitted in different
    directions
A
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9
Q

Refraction

  • Refraction is the change in direction of a wave passing between 2 tissues where there is a change of wave speed
  • It only occurs when the incident beam strikes the tissue boundary obliquely (there is no refraction for normal incidence)
  • The transmitted wave moves in a different direction from the incident wave
  • The magnitude of the change in direction depends on the ratio of the wave speeds in the 2 tissues
  • The reflected wave is unaffected
A
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10
Q

US Beam Attenuation

  • As ultrasound pulses (and reflected echoes) travel
    through tissue, their intensity is reduced or
    attenuated.
A
  • Attenuation of the US beam is due to:
    ➢ Reflection and scattering removes/redirects energy
    from the US beam
    ➢ Beam divergence – energy is spread over a wider area thus reducing intensity
    ➢ Frictional losses – results in absorption of US energy by tissue and is converted into heat.
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11
Q

US Beam Attenuation
* The intensity of any US beam decreases exponentially
with depth in tissue.
* Attenuation increases with US frequency

A
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12
Q

US Attenuation Coefficients

NEED TO KNOW

  • US attenuation coefficients are quoted in units of dB/cm/MHz
  • Soft tissue attenuation coefficient ~0.8dB/cm/MHz:
    – 0.8 dB/cm at 1 MHz (17% reduction in intensity per cm)
    – 4 dB/cm at 5MHz (60% reduction in intensity per cm)
A
  • Water/blood attenuation coefficient
    ~0.15dB/cm/MHz:
    – 0.15 dB/cm at 1 MHz (3% reduction in intensity per cm)
    – 0.45 dB/cm at 5MHz (10% reduction in intensity per cm)
  • Bone attenuation coefficient ~15dB/cm/MHz:
    – 15 dB/cm at 1 MHz (97% reduction in intensity per cm)
  • Lung attenuation coefficient >30dB/cm/MHz
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13
Q

Ultrasound Transducer

  • An ultrasound transducer converts electrical energy into ultrasound waves (mechanical energy) & vice versa
  • Transducer acts as both the source & detector of US waves using the Piezoelectric effect
  • US production - alternating voltage applied to the end faces of the transducer crystal causes it to vibrate
A
  • US detection – waves arriving at the crystal face cause it to vibrate & generate an alternating voltage
  • PZT (lead zirconate titanate) often used as the transducer crystal
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14
Q

Ultrasound Transducer

  • The crystal is backed with a damping material to prevent the crystal from vibrating
  • This is important for the production of short pulses
  • An “acoustic window” is fitted to the front surface of the transducer to protect the crystal from damage and transmit as much of the US radiation as possible into the patient
A
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15
Q

ACOUSTIC FIELDS

  • US imaging is performed in the near field as far as the focal zone.
  • The shape of the beam is affected by the frequency of the US radiation and
    the diameter of the transducer crystal.
  • The near field is narrower at higher frequencies

Unfocused beam - parallel - then diverges
Focused converges and then diverges

A
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16
Q

Basis for US Imaging

  • All US imaging derives spatial information about the location of tissue
    boundaries using the “pulse echo” principle
  • A short pulse of US (typically ~1µ sec in duration) is transmitted into the body
    & the time taken for it to return to the transducer is measured
  • If the velocity of the pulse in tissue is known (or assumed) then the depth of
    the reflecting structure relative to the transducer can be determined
A
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17
Q

US Pulses

  • A pulse is a short burst of US radiation
  • Each pulse has finite duration and size (length)
  • Length is typically 2-3 wavelengths
  • Duration is typically ~1s
  • The number of pulses emitted each second by the transducer is called the
    pulse repetition frequency (PRF)
  • In clinical US imaging the PRF is typically 3-6kHz
A
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18
Q

US Scanning
* There are various ways data can be recorded
➢ A-mode
➢ B-mode
➢ M-mode
➢ CW Doppler
➢ Pulsed Doppler
➢ Harmonic imaging

A
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19
Q

A-Mode Scan

  • In A-mode (“A” = “amplitude”) pulses are sent down a single scan line and
    produces a graphical display, not an image
  • Depth is represented by the horizontal axis of the display
  • The amplitude of each echo is represented on the vertical axis
A
  • A-scans can accurately depict the depth of structures in the patient
  • Used in opthalmology to measure the axial length of the eye & in obstetrics to
    measure the size of the fetal head
  • A-mode uses high US frequency (typically 10MHz) to improve accuracy
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20
Q

B-Mode Scan

Brightness Mode

We fire a scan line into the patient, we’re going to get partial reflection at these two positions. And in the image, we see two dots which match the depth of the reflecting surfaces. The brightness of the dots reflects the magnitude of the echo at those places, and then we do that for subsequent lines across the image.

A
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21
Q

M Mode Scan

stands for motion. With this, it’s like a B mold scan, except you only scanned on a single line, so there’s a single scan line.

A
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22
Q

Time Gain Compensation

  • Depth of echo = Return time x wave speed / 2
  • Echoes arriving later are from a greater depth and have suffered greater attenuation
  • In TGC pulses are amplified according to when they arrive at the
    transducer
  • With TGC all echoes from the same tissue boundary will have the same
    brightness – regardless of depth
A
23
Q

US Transducers / Probes

  • Used to generate & detect US pulses
  • Modern transducers contain an array of 64 to 512 small piezoelectric crystals
    (usually PZT)
  • The crystals have a thickness = 1⁄2 wavelength of emitted US waves
A
  • High frequency probes have thin crystals (0.1mm at 7.5MHz)
  • Low frequency prob
    es have thick crystals (0.5mm at 1.5MHz)
  • There are 3 main types of transducers/probes
24
Q

Linear Array Transducer

  • A linear array probe consists of 256 to 512 discrete transducer elements.
  • A small group of adjacent elements are simultaneously activ
    ated to create a scan
    line
  • Sequential activation of adjacent groups of crystals creates a series of scan lines
    across the transducer surface.
  • All scan lines are emitted at 90 degrees to the face of the probe
A
25
Q

Linear Array Transducer

  • These probes generate a limited FoV which is rectangular
  • Tend to operate at higher frequencies (>5MHz) to improve resolution but
    only image superficial structures (1-4cm depth of view)
A
  • Useful for scanning superficial structures such as the neck, breast, scrotum and extremities, or paediatric studies
26
Q

Curvilinear Array Transducer

  • These probes have a wider FoV than linear array probes
  • Tend to operate at lower frequencies (2-5MHz) to allow the beam to penetrate to greater depth (typically 4-8cm)
A
  • Used for abdominal, fetal, and obstetric studies
  • Diverging scan lines with depth results in reduced lateral resolution
26
Q

Phased Array Transducer

  • Have a smaller footprint than linear
    array probes
  • There are typically 64 to 128 crystal
    elements.
  • In a phased array all segments are fired
    simultaneously
A
  • Short, predetermined delays are
    introduced into the timing of the
    triggering of the crystal elements
  • This generates a scan line that can be
    steered in different directions and/or
    focused
27
Q

Phased Array Transducer

  • Phased arrays generate sector FoVs
  • Tend to operate at low frequencies (1-
    5MHz)
  • Useful for cardiac imaging (small
    footprint means the probe can scan
    between the ribs)
A
28
Q

Lateral Resolution

Lateral resolution in B-Mode scans depends on:

Beam width
* Best resolution is in the focal zone

Number of scan lines per frame
* More scan lines provides better resolution,
but each frame takes longer to acquire

A

Frequency of the US radiation
* Resolution is better (beam width is
narrower) at higher frequency

Lateral resolution is typically:
2.5mm at 3MHz

1mm at 10MHz

29
Q

Lateral Resolution is DEPTH DEPENDANT

In the near and far fields, the beam
is wider than it is at the focal
distance.

Two point reflectors separated by
the same distance will appear as a
single structure in the image in the
near & far field, but will be resolved
at the focal distance.

A
30
Q

Axial Resolution

Axial resolution in B-Mode scans is determined by the spatial pulse length (SPL)

Axial resolution = 1/2 x SPL
Axial resolution improves with increasing frequency
Axial resolution is not depth dependent

A
31
Q

Doppler Effect

A
32
Q

Doppler Effect

A
33
Q

Pulsed Wave (PW) Doppler

GIVES DEPTH and FREQUENCY SHIFT

  • A single transducer emits a pulsed beam & detects the frequency shift in detected echoes
  • The pulse-echo principle is used, so depth information is available
  • PW Doppler is usually combined with B-mode scanning
    ➢ Can select a specific range of depths (“range gate”) to sample the
    Doppler signal from
    ➢ Doppler angle can be estimated from B-mode scan
A
  • The pulsed nature of the beam limits the maximum Doppler frequency shift that can be detected
  • Max detectable freq shift = 1⁄2 PRF
  • Aliasing is an artifact that occurs when the freq shift > 1⁄2 PRF
  • Need a high PRF to examine high flow velocities, which will limit the depth of the range gate
  • Can present Doppler information as either a colour flow image or as a
    spectrum
34
Q

Continuous Wave (CW) Doppler

  • CW Doppler requires 2 transducers
  • 1 transmits continuously, the other
    receives continuously
  • Doppler signal arises from where the
    beams overlap
  • Because the pulse-echo principle is not
    used there is NO DEPTH information
A
  • CW probes emit narrow bandwidth US
  • Can measure very high flow velocities
  • Doppler frequency shift can be
    converted into an audible signal and
    also as a velocity spectrum graph
  • Often used in cardiac scanners to
    investigate the high velocities in the
    aorta

Shift in KHz = audible range

35
Q

Key points for pulsed wave doppler

A
  • Max detectable freq shift = 1⁄2 PRF
  • Aliasing is an artifact that occurs when the freq shift > 1⁄2 PRF
36
Q

Colour Flow Doppler

  • Combined with B-mode imaging
  • Operator selects a colour box where the Doppler signal will be generated
  • Pulsed Doppler (PD) information is only received from the region within the colour box
  • Transducer switches rapidly between B-mode & Doppler mode
    (duplex scanning)
A
  • Doppler pulses are 3-4 times longer than B-mode pulses (for improved accuracy of detection of frequency shift)
  • Multiple Doppler pulses (10 or more) must be sent down each scan line in the colour box to obtain an accurate measure of Doppler shift
  • For each point along a scan line in the colour box, the mean Doppler shifted velocity is calculated and assigned a colour
    which is mapped on the B-mode image

GIVES YOU MAGNITUDE AND DIRECTION

37
Q

Colour Flow Doppler

  • Colour coded flow information is superimposed on a B-mode image
  • Live image, updated in real time displaying overall view of flow in a region
  • Displays direction & magnitude of blood flow
  • Red & blue indicate flow in different directions
  • BART – Blue Away, Red Towards the probe
  • Aliasing occurs if Doppler frequency > 1⁄2 PRF
A
38
Q

Power Doppler

  • A form of colour flow imaging
  • Displays magnitude of blood flow only – no directional
    information
  • No aliasing artifacts
  • Good for detecting low flow rates
A
39
Q

Spectral Doppler Display

  • Usually combined with Colour Flow imaging
  • A single Doppler beam axis is selected from the colour flow image
  • A sample volume is positioned along the axis
A
  • Detailed flow information is generated from within the sample volume and displayed as a spectrum
  • Combination of colour flow & spectral display is known as Triplex scanning
40
Q

Harmonic Imaging

  • The profile of an US wave becomes distorted as it travels through tissue.
  • The wave speed is actually dependent on pressure, which is different during
    the compression & rarefaction parts of the cycle.
  • The wave travels faster during compression & slower during rarefaction
A
  • As a result the wave profile changes and this becomes more evident the
    further the wave travels.
  • The change in wave profile enhances frequency content at multiples of the
    transmit frequency (harmonic frequencies).
40
Q

Spectral Doppler Display

  • A display of the spectrum of Doppler frequencies (flow velocities) on the vertical axis vs time on the horizontal axis
  • Examines detailed flow information along a single scan line
  • Allows detailed analysis of distribution of flow
A
  • Good temporal resolution – can examine flow waveform
  • Allows calculations of velocity and indices
  • Can be used for CW or PW Doppler
41
Q

Harmonic Imaging

  • In Harmonic Imaging, the returning signal (C) is actually a combination of
    frequencies.
  • It contains not only the fundamental signal that was originally
    transmitted (A), but also the harmonic signal (B), which is twice A’s
    frequency.
A

Relative changes in the fundamental and harmonic signal with depth

42
Q

The production of harmonic waves is greatest where the beam intensity is
highest - along the central axis of the beam.

Little or no harmonics are produced by weaker waves, such as those from
the edges of the US beam, scattered echoes, side lobes and reverberations.

A
43
Q

Advantages of Harmonic Imaging

  • Better contrast – weak signals from scatter are not detected.
  • Better lateral resolution and slice thickness - Harmonic waves are predominantly generated at the centre of the US beam, which narrows the imaging plane
  • Artifact reduction (reverberation and side lobe) which have their origins in weaker beams
A
  • Greater acoustic enhancement beyond fluid-filled structures
  • Improved imaging of deeper tissue: preferential generation of harmonic waves in deeper tissue can improve image quality in obese patients as long as tissue attenuation effects do not
    dominate
  • Cons – poorer axial resolution due to a reduce bandwidth used in HI (longer spatial pulse length)
43
Q

US Contrast Agents

  • Gas-filled micro-bubbles injected into the blood.
  • Micro-bubbles remain in the circulation for a short
    period of time.
  • Increased backscattering from micro-bubbles due to
    large acoustic impedance differences.
A
  • The bubbles give increased signal from blood.
  • Allows detection of blood flow in difficult cases.
  • Bubbles are typically 2-5µ m in diameter
  • Filled with air or fluoropropane
44
Q

US Artifacts

  • Reverberation artifact – multiple reflections between adjacent tissue boundaries creates sequential echoes at
    increasing depths in the image
  • Comet tail artifact – as above
  • Ring down artifact – resonation of liquid trapped between gas bubbles is portrayed as a continuous streak extending
    downwards
A
  • Speed of sound artifact – structures are depicted at the wrong depth in the image due to assumption c=1540m/s
  • Acoustic enhancement - appears as a bright band extending from an object of low attenuation
  • Acoustic shadowing - a dark or hypoechoic band deep to a
    beyond a highly attenuating structure
45
Q

Reverberation Artifact

Echoes generated from two parallel
highly reflective surfaces may be
repeatedly reflected back and forth
before returning to the transducer for
detection. When this occurs, multiple
echoes are recorded and displayed.

A

The echo that returns to the
transducer after a single reflection will
be displayed in the proper location.
The sequential echoes will take longer
to return & will be erroneously placed
at increased distances from the
transducer.

46
Q

Comet Tail Artifact

  • Comet tail artifact is a form of
    reverberation, where the two reflective
    interfaces (& echoes) are very closely
    spaced.
  • On the display, the sequential echoes may be so close together that individual signals are not perceivable. Also, the later echoes will have decreased amplitude due to attenuation, resulting in decreased width. The result is an artifact with a triangular, tapered shape.
A
  • This artifact is often caused by small
    calcifications and metal objects (foreign
    bodies and surgical clips).
47
Q

Ring Down Artifact
* Ring down artifacts resemble comet tail artifacts in appearance.

  • The artifact is caused by an interaction of the US beam with clusters of gas bubbles. When the US beam reaches the gas bubbles, it is capable of exciting the liquid trapped between the bubbles, which causes the liquid to resonate. These vibrations create a continuous sound wave which is transmitted back to the receiver.
A
  • Because the resonant wave is emitted continuously (not as a pulse) it is portrayed as a streak extending posteriorly from the gas cluster.
48
Q

Speed of Sound Artifact

When sound travels through material
with a velocity significantly slower than
the assumed 1540 m/sec, the returning
echo will take longer to return to the
transducer.

The image processor assumes that the
length of time for a single round trip of
an echo is related only to the distance
travelled by the echo.

The echoes are thus displayed deeper on
the image than they really are.

A
49
Q

Refraction Artifact

When an US beam is obliquely incident on
the boundary between two tissues with
different speeds of sound (eg. fat and muscle) refraction occurs. The direction of the US beam is altered as it crosses the boundary.

The image processor assumes all emitted
pulses travel in straight lines from the
transducer.

Hence the position of the reflector (black
circle) will be incorrectly placed in the image
(dotted circle).

A
50
Q

Acoustic Enhancement

A
51
Q

Acoustic Shadowing

A
52
Q

Ultrasound Safety

US is generally safe (non-ionising radiation), but can interact with
human tissue to create:

Thermal effects:
➢ Tissue heating due to absorption of US radiation. Greatest thermal risks apply to:

▪ Embryo < 8 week post conception
▪ Head, brain or spine of any neonate
▪ The eye

A

Mechanical effects:

➢ “cavitation” (formation & collapse of bubbles when dissolved gases come out of solution)

➢ likelihood of cavitation is greater for large output settings and
lower frequencies

53
Q

Thermal Index (TI)

  • TI provides an onscreen indication of the relative potential for a tissue temperature rise produced after long exposure
  • TI = W / Wdeg where W is the acoustic power of the beam at a specified
    point, and Wdeg is the power required for a maximum temperature rise of
    1°C anywhere in the beam.

(TI is estimated by the machine and can be in error by as much as x2)

  • Different values for soft tissue (TIS) & bone (TIB)
A
  • Pulsed Doppler techniques generally involve greater temporal
    average intensities and powers than B-mode, and hence greater
    heating potential.

LEARN:

  • No restriction on exposure time for TIS ≤ 0.7
  • Embryo/fetal scanning not recommended for TIS > 3.0
54
Q

Mechanical Index (MI)

The MI is an on-screen indicator of the relative potential for ultrasound to induce an adverse non-thermal bio-effect

MI α (Peak Rarefaction Pressure) / √(operating frequency)

Non-thermal effects most likely in lungs & intestines (contain gas) and also when using US contrast agents.

A

MI≤0.3: No restriction on exposure times

MI>0.3: Possibility of minor damage to lung or intestine in neonates

MI>0.7: should be used with caution in the presence of contrast agents

BMUS safety guidelines available at:

https://www.bmus.org/static/uploads/resources/BMUS-Safety-
Guidelines-2009-revision-FINAL-Nov-2009.pdf