Racemic epinephrine Flashcards
What is racemic Epinephrine ?
It irritates the sympathetic nervous system (sympathomimetic)
Mechanism of action of racemic epinephrine?
Causes bronchodilation (stimulates beta2)
Reduces airway resistance
Inhibits histamine release (inflammatory response)
Why give racemic epi ?
Bronchospasm, COPD / asthma (open up bronchioles)
Croup
Laryngeal edema
Why would you not give racemic epi?
Htn
Cardiovascular disease
epiglottitis
Side effects of racemic epi?
Headache Anxiety Restlessness Fear Nervousness Palpitations Tachycardia
What if I mix it with other drugs ?
Beta blockers may inhibit the effects
Dose for racemic epi?
Adult- 5ml (1%) in 5mL of saline over 15 min
Pedi- under 4: 0.25 ml (2.25) in 3 mL over 15 min
Over 4: 0.5 mL (2.25) in 3 mL over 15 min
What is the pregnancy category ?
C, weigh benefits vs risk
NOTE
Using too much can cause bronchospasm
can have rebound effect when wearing off